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Details on Person 25(OH)D translocates from lysosomal lumen to cytosol

Class:Id	BlackBoxEvent:209766
_displayName	25(OH)D translocates from lysosomal lumen to cytosol
_doRelease	TRUE
_timestamp	2025-07-03 21:44:26
authored	[InstanceEdit:378946] Jassal, Bijay, 2008-10-01
compartment	[Compartment:70101] cytosol [Compartment:161320] lysosomal lumen
created	[InstanceEdit:209769] Jassal, B, 2008-01-07 09:34:20
edited	[InstanceEdit:352314] Jassal, B, 2008-06-02 10:50:11
goBiologicalProcess	[GO_BiologicalProcess:258911] intracellular lipid transport
input	[SimpleEntity:350136] 25(OH)D [lysosomal lumen]
literatureReference	[LiteratureReference:8963853] The human HSP70 family of chaperones: where do we stand?
modified	[InstanceEdit:350121] Jassal, Bijay, 2008-05-14 [InstanceEdit:352338] Jassal, B, 2008-06-02 16:22:02 [InstanceEdit:352341] Jassal, B, 2008-06-02 16:25:21 [InstanceEdit:380824] Jassal, Bijay, 2008-11-17 [InstanceEdit:6807513] D'Eustachio, Peter, 2015-11-02 [InstanceEdit:8963878] Jassal, Bijay, 2017-02-13 [InstanceEdit:8963880] Jassal, Bijay, 2017-02-13 [InstanceEdit:9028764] Jassal, Bijay, 2017-11-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9959973] D'Eustachio, Peter, 2025-07-03
name	25(OH)D translocates from lysosomal lumen to cytosol
output	[SimpleEntity:209804] 25(OH)D [cytosol]
precedingEvent	[BlackBoxEvent:350158] LGMN hydrolyzes GC, releasing CUBN and 25(OH)D [Homo sapiens] [BlackBoxEvent:209760] Endocytic translocation of CUBN:GC:25(OH)D to lysosomal lumen [Homo sapiens]
releaseDate	2008-06-30
reviewed	[InstanceEdit:351775] D'Eustachio, P, 2008-05-28 08:30:54
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:361871] R-HSA-209766.6
summation	[Summation:350113] Once out of the lysosome, 25-hydroxyvitamin D (calcidiol, 25...
(hasEvent)	[Pathway:196791] Vitamin D (calciferol) metabolism [Homo sapiens]
(precedingEvent)	[Reaction:209868] CYP27B1 hydroxylates 25(OH)D to 1,25(OH)2D [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9780454] Update Tracker - [BlackBoxEvent:209766] 25(OH)D translocates from lysosomal lumen to cytosol - v63:[modifyText] [_UpdateTracker:9781972] Update Tracker - [BlackBoxEvent:209766] 25(OH)D translocates from lysosomal lumen to cytosol - v60:[add_removeLiteratureReference, modifyText]
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