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Details on Person CNK is phosphorylated by an unknown kinase

Class:Id	Reaction:209337
_displayName	CNK is phosphorylated by an unknown kinase
_doRelease	FALSE
_timestamp	2017-06-27 17:35:14
authored	[InstanceEdit:386949] Williams, MG, 2008-10-09 16:49:12
catalystActivity	[CatalystActivity:208923] protein tyrosine kinase activity of unknown kinase [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:205618] Williams, MG, 2007-10-30 11:44:05
figure	[Figure:947971] /figures/DrosRasRafERKA29.jpg
input	[Complex:206609] CNK:14-3-3epsilon dimer:Phospho (2 sites) PHL:Phospho (2 sites) KSR:14-3-3epsilon dimer:AVE:DSOR1:CK2:PAR-1:PP2A-29B:MTS [cytosol] [Drosophila melanogaster] [SimpleEntity:113592] ATP [cytosol]
literatureReference	[LiteratureReference:208095] Src42 binding activity regulates Drosophila RAF by a novel CNK-dependent derepression mechanism [LiteratureReference:208271] CNK, a RAF-binding multidomain protein required for RAS signaling
modified	[InstanceEdit:386957] Williams, MG, 2008-11-27 14:37:44 [InstanceEdit:947989] Williams, MG, 2010-09-14 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9010639] D'Eustachio, Peter, 2017-06-27
name	CNK is phosphorylated by an unknown kinase
output	[Complex:206996] Phospho CNK:14-3-3epsilon dimer:Phospho (2 sites) PHL:Phospho (2 sites) KSR:14-3-3epsilon dimer:AVE:DSOR1:CK2:PAR-1:PP2A-29B:MTS [cytosol] [Drosophila melanogaster] [SimpleEntity:29370] ADP [cytosol]
precedingEvent	[Reaction:209234] 14-3-3epsilon dimers bind to KSR and PHL [Drosophila melanogaster] [Reaction:209270] PKA-C1 phosphorylates PHL in the vicinity of its C1 domain [Drosophila melanogaster]
species	[Species:56210] Drosophila melanogaster
stableIdentifier	[StableIdentifier:8917894] R-DME-209337.1
summation	[Summation:206465] Upon growth factor stimulation, Tyr1163 of Connector Enhance...
(hasEvent)	[Pathway:209437] Formation of the multi-kinase 'signalling complex' [Drosophila melanogaster]
(precedingEvent)	[Reaction:209325] SRC42A kinase binds to phosphorylated CNK [Drosophila melanogaster]
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No pathways have been reviewed or authored by CNK is phosphorylated by an unknown kinase (209337)