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Details on Person Phosphorylated human RAF1 binds to the plasma membrane through its C1 domain

Class:Id	Reaction:209334
_displayName	Phosphorylated human RAF1 binds to the plasma membrane through its C1 domain
_doRelease	FALSE
_timestamp	2016-07-15 23:48:55
authored	[InstanceEdit:386944] Williams, MG, 2007-10-26 16:49:12
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:205618] Williams, MG, 2007-10-30 11:44:05
figure	[Figure:947930] /figures/DrosRasRafERKA40.jpg
input	[EntityWithAccessionedSequence:206028] p-S621-RAF1 [cytosol] [Homo sapiens]
literatureReference	[LiteratureReference:208351] Mutational analysis of Raf-1 cysteine rich domain: requirement for a cluster of basic aminoacids for interaction with phosphatidylserine [LiteratureReference:208163] Dephosphorylation of Ser-259 regulates Raf-1 membrane association
modified	[InstanceEdit:350535] Williams, MG, 2008-05-19 14:36:52 [InstanceEdit:386962] Williams, MG, 2008-11-27 15:15:51 [InstanceEdit:947989] Williams, MG, 2010-09-14 [InstanceEdit:948073] Williams, MG, 2010-09-16 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:8879177] Wu, G, 2016-07-15
name	Phosphorylated human RAF1 binds to the plasma membrane through its C1 domain
output	[EntityWithAccessionedSequence:206222] p-S621-RAF1 [plasma membrane] [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8879951] R-HSA-209334.1
summation	[Summation:948068] In humans, the exposed C1 domain of phosphorylated RAF1 aka ...
(hasEvent)	[Pathway:481001] Ras/Raf/ERK pathway - Inferred Events
(inferredFrom)	[Reaction:209202] PHL and KSR bind to the plasma membrane [Drosophila melanogaster]
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No pathways have been reviewed or authored by Phosphorylated human RAF1 binds to the plasma membrane through its C1 domain (209334)