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Details on Person UPD ligand binds to the HOP:DOME:DOME:HOP complex and activates HOP

Class:IdReaction:209255
_displayNameUPD ligand binds to the HOP:DOME:DOME:HOP complex and activates HOP
_doReleaseTRUE
_timestamp2017-08-10 21:58:20
authored[InstanceEdit:386954] Williams, MG, 2006-11-02 16:49:12
compartment[Compartment:984] extracellular region
[Compartment:876] plasma membrane
created[InstanceEdit:205673] Williams, MG, 2006-11-03 15:40:44
edited[InstanceEdit:205673] Williams, MG, 2006-11-03 15:40:44
figure[Figure:208794] /figures/ADrosJAKSTAT03.jpg
input[DefinedSet:206555] UPD [extracellular region] [Drosophila melanogaster]
[Complex:206971] HOP:DOME:DOME:HOP [plasma membrane] [Drosophila melanogaster]
literatureReference[LiteratureReference:208179] mom identifies a receptor for the Drosophila JAK/STAT signal transduction pathway and encodes a protein distantly related to the mammalian cytokine receptor family
[LiteratureReference:208055] Characterisation of Upd2, a Drosophila JAK/STAT pathway ligand
[LiteratureReference:208064] A novel functional activator of the Drosophila JAK/STAT pathway, unpaired2, is revealed by an in vivo reporter of pathway activation
[LiteratureReference:208109] Signaling role of hemocytes in Drosophila JAK/STAT-dependent response to septic injury
modified[InstanceEdit:350540] Williams, MG, 2008-05-19 14:43:09
[InstanceEdit:386964] Williams, MG, 2008-11-27 15:41:07
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:9015677] D'Eustachio, Peter, 2017-08-10
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameUPD ligand binds to the HOP:DOME:DOME:HOP complex and activates HOP
output[Complex:206753] HOP:DOME:UPD:DOME:HOP [plasma membrane] [Drosophila melanogaster]
precedingEvent
releaseDate2009-03-12
reviewed[InstanceEdit:386947] Perrimon, N, 2008-01-16 11:04:04
reviewStatus[ReviewStatus:9821382] five stars
species[Species:56210] Drosophila melanogaster
stableIdentifier[StableIdentifier:8918019] R-DME-209255.2
summation[Summation:206510] The UPD (OS, UPD2, UPD3) family of ligands bind to the DOME:...
(hasEvent)[Pathway:209209] Formation of the activated receptor complex [Drosophila melanogaster]
(precedingEvent)[Reaction:209336] Activated HOP is autophosphorylated and/or transphosphorylated [Drosophila melanogaster]
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