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Details on Person CI75 inhibits transcription

Class:Id	Reaction:209252
_displayName	CI75 inhibits transcription
_doRelease	TRUE
_timestamp	2018-03-09 00:11:56
authored	[InstanceEdit:386946] Williams, MG, 2006-12-07 16:49:12
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:205626] Williams, MG, 2006-12-08 11:30:45
edited	[InstanceEdit:5490376] Williams, MG, 2014-05-20
figure	[Figure:216247] /figures/DrosHHB14.jpg
input	[EntityWithAccessionedSequence:205741] CI75 [nucleoplasm] [Drosophila melanogaster]
literatureReference	[LiteratureReference:208353] Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor [LiteratureReference:208132] Hedgehog controls limb development by regulating the activities of distinct transcriptional activator and repressor forms of Cubitus interruptus [LiteratureReference:216243] The repressor and activator forms of Cubitus interruptus control Hedgehog target genes through common generic gli-binding sites
modified	[InstanceEdit:216199] Williams, MG, 2008-03-11 15:41:17 [InstanceEdit:350488] Williams, MG, 2008-05-19 14:06:00 [InstanceEdit:386957] Williams, MG, 2008-11-27 14:37:44 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9024533] Matthews, Lisa, 2017-10-05 [InstanceEdit:9038602] D'Eustachio, Peter, 2018-03-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CI75 inhibits transcription
output	[EntityWithAccessionedSequence:205741] CI75 [nucleoplasm] [Drosophila melanogaster]
precedingEvent	[Reaction:209370] CI75 transports from the cytosol to the nucleus [Drosophila melanogaster] [BlackBoxEvent:209278] Ubiquitinated and phosphorylated CI is partially degraded by the proteasome complex [Drosophila melanogaster]
releaseDate	2017-09-12
reviewed	[InstanceEdit:386945] Kalderon, D, 2008-03-17 11:00:25
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:56210] Drosophila melanogaster
stableIdentifier	[StableIdentifier:8913645] R-DME-209252.4
summation	[Summation:206339] Upon arrival in the nucleus, truncated Cubitus Interruptus (...
(hasEvent)	[Pathway:209446] N-HH ligand not bound to PTC receptor complex [Drosophila melanogaster]
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No pathways have been reviewed or authored by CI75 inhibits transcription (209252)