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Details on Person SEV receptor autophosphorylates and is activated at the plasma membrane

Class:Id	Reaction:209233
_displayName	SEV receptor autophosphorylates and is activated at the plasma membrane
_doRelease	FALSE
_timestamp	2017-06-27 17:38:16
authored	[InstanceEdit:386944] Williams, MG, 2007-10-26 16:49:12
catalystActivity	[CatalystActivity:208945] protein tyrosine kinase activity of SEV [plasma membrane]
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:205618] Williams, MG, 2007-10-30 11:44:05
figure	[Figure:947879] /figures/DrosSevB02.jpg
input	[Complex:206885] BOSS:SEV dimer [plasma membrane] [Drosophila melanogaster] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol]
literatureReference	[LiteratureReference:208108] Extracellular domain of the boss transmembrane ligand acts as an antagonist of the sev receptor [LiteratureReference:208382] Biochemical and genetic analysis of the Drk SH2/SH3 adaptor protein of Drosophila [LiteratureReference:208310] Structure and autoregulation of the insulin-like growth factor 1 receptor kinase [LiteratureReference:208332] Autophosphorylation of the insulin-like growth factor I receptor cytoplasmic domain [LiteratureReference:179887] Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor
modified	[InstanceEdit:386963] Williams, MG, 2008-11-27 15:33:38 [InstanceEdit:947989] Williams, MG, 2010-09-14 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9010639] D'Eustachio, Peter, 2017-06-27
name	SEV receptor autophosphorylates and is activated at the plasma membrane
output	[Complex:206949] BOSS:Phospho SEV dimer [plasma membrane] [Drosophila melanogaster] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol]
precedingEvent	[Reaction:209260] In the plasma membrane of an adjacent cell, BOSS ligand binds across to SEV dimer receptor [Drosophila melanogaster]
species	[Species:56210] Drosophila melanogaster
stableIdentifier	[StableIdentifier:8883048] R-DME-209233.1
summation	[Summation:206447] Sevenless (SEV) receptor dimerisation juxtaposes the cytopla...
(hasEvent)	[Pathway:209401] Assembly of the SEV complex [Drosophila melanogaster]
(precedingEvent)	[Reaction:209263] DRK:SOS complex binds to phosphorylated SEV receptor at the plasma membrane [Drosophila melanogaster] [Reaction:209375] DRK:DOS complex binds to phosphorylated SEV receptor at the plasma membrane [Drosophila melanogaster]
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No pathways have been reviewed or authored by SEV receptor autophosphorylates and is activated at the plasma membrane (209233)