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Details on Person Phosphorylated RL kinase binds to MKP3 phosphatase

Class:Id	Reaction:209197
_displayName	Phosphorylated RL kinase binds to MKP3 phosphatase
_doRelease	FALSE
_timestamp	2017-06-27 17:37:18
authored	[InstanceEdit:386949] Williams, MG, 2008-10-09 16:49:12
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:205618] Williams, MG, 2007-10-30 11:44:05
figure	[Figure:947882] /figures/DrosRasRafERKA110.jpg
input	[EntityWithAccessionedSequence:206254] Phospho (2 sites) RL [cytosol] [Drosophila melanogaster] [EntityWithAccessionedSequence:206056] MKP3 [cytosol] [Drosophila melanogaster]
literatureReference	[LiteratureReference:208267] Isolation and characterization of a Drosophila homologue of mitogen-activated protein kinase phosphatase-3 which has a high substrate specificity towards extracellular-signal-regulated kinase [LiteratureReference:208288] MKP-3 has essential roles as a negative regulator of the Ras/mitogen-activated protein kinase pathway during Drosophila development
modified	[InstanceEdit:386962] Williams, MG, 2008-11-27 15:15:51 [InstanceEdit:947758] Williams, MG, 2010-09-13 [InstanceEdit:947989] Williams, MG, 2010-09-14 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9010639] D'Eustachio, Peter, 2017-06-27
name	Phosphorylated RL kinase binds to MKP3 phosphatase
output	[Complex:206975] Phospho (2 sites) RL:MKP3 [cytosol] [Drosophila melanogaster]
precedingEvent	[Reaction:209164] RL kinase is phosphorylated and activated by phosphorylated DSOR1 kinase and dissociates from KSR [Drosophila melanogaster] [Reaction:209335] Activated PHL kinase domain phosphorylates DSOR1 kinase and activates it [Drosophila melanogaster] [Reaction:947713] Phosphorylated RL kinase phosphorylates and dissociates from LK6 kinase [Drosophila melanogaster] [Reaction:947726] Phosphorylated RL kinase binds to LK6 kinase [Drosophila melanogaster]
species	[Species:56210] Drosophila melanogaster
stableIdentifier	[StableIdentifier:8931242] R-DME-209197.1
summation	[Summation:206501] Towards the N-terminal end of the dual-specificity Mitogen-a...
(hasEvent)	[Pathway:209429] Dephosphorylation of RL kinase [Drosophila melanogaster]
(precedingEvent)	[Reaction:209203] Phosphorylated RL kinase is dephosphorylated and deactivated by MKP3 phosphatase [Drosophila melanogaster]
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