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Details on Person CSW phosphatase binds to phosphorylated DOS

Class:Id	Reaction:209166
_displayName	CSW phosphatase binds to phosphorylated DOS
_doRelease	FALSE
_timestamp	2017-06-27 17:35:21
authored	[InstanceEdit:386944] Williams, MG, 2007-10-26 16:49:12
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:205618] Williams, MG, 2007-10-30 11:44:05
figure	[Figure:947960] /figures/DrosSevB08.jpg
input	[Complex:206769] BOSS:Phospho SEV dimer:DRK:Phospho (multi-site) DOS [plasma membrane] [Drosophila melanogaster] [EntityWithAccessionedSequence:206073] CSW [cytosol] [Drosophila melanogaster]
literatureReference	[LiteratureReference:208106] Recruitment of the protein tyrosine phosphatase CSW by DOS is an essential step during signaling by the sevenless receptor tyrosine kinase [LiteratureReference:208128] Daughter of sevenless is a substrate of the phosphotyrosine phosphatase Corkscrew and functions during sevenless signaling [LiteratureReference:208215] Mutational analysis of the SRC homology 2 domain protein-tyrosine phosphatase Corkscrew
modified	[InstanceEdit:386957] Williams, MG, 2008-11-27 14:37:44 [InstanceEdit:947989] Williams, MG, 2010-09-14 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9010639] D'Eustachio, Peter, 2017-06-27
name	CSW phosphatase binds to phosphorylated DOS
output	[Complex:206758] BOSS:Phospho SEV dimer:DRK:Phospho (multi-site) DOS:CSW [plasma membrane] [Drosophila melanogaster]
precedingEvent	[Reaction:209317] Activated phosphorylated SEV receptor phosphorylates DOS [Drosophila melanogaster] [Reaction:209375] DRK:DOS complex binds to phosphorylated SEV receptor at the plasma membrane [Drosophila melanogaster]
species	[Species:56210] Drosophila melanogaster
stableIdentifier	[StableIdentifier:8924470] R-DME-209166.1
summation	[Summation:206514] The SH2 domains of the phosphotyrosine phosphatase, Corkscre...
(hasEvent)	[Pathway:209399] Formation of DOS scaffolding protein-containing complexes [Drosophila melanogaster]
(precedingEvent)	[Reaction:209345] CSW phosphatase dephosphorylates phosphorylated DOS [Drosophila melanogaster]
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