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Details on Person Human APC is finally phosphorylated by Murine GSK3beta

Class:Id	Reaction:209144
_displayName	Human APC is finally phosphorylated by Murine GSK3beta
_doRelease	TRUE
_timestamp	2018-08-14 12:44:21
authored	[InstanceEdit:386950] Williams, MG, 2006-07-26 16:49:12
catalystActivity	[CatalystActivity:208891] protein serine/threonine kinase activity of GSK3beta [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:205655] Williams, MG, 2006-10-24 12:52:33
figure	[Figure:208494] /figures/BDrosWing05a.jpg
input	[EntityWithAccessionedSequence:205825] p-5S-APC-1 [cytosol] [Homo sapiens] [SimpleEntity:113592] ATP [cytosol]
isChimeric	TRUE
literatureReference	[LiteratureReference:196265] Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation
modified	[InstanceEdit:209093] Williams, MG, 2007-07-12 09:35:45 [InstanceEdit:209046] Williams, MG, 2007-10-16 10:48:16 [InstanceEdit:350493] Williams, MG, 2008-05-19 14:11:36 [InstanceEdit:386959] Williams, MG, 2008-11-27 14:56:57 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9024533] Matthews, Lisa, 2017-10-05 [InstanceEdit:9028862] Matthews, Lisa, 2017-11-13 [InstanceEdit:9616759] Matthews, Lisa, 2018-08-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Human APC is finally phosphorylated by Murine GSK3beta
output	[EntityWithAccessionedSequence:205944] p-6S-APC-1 [cytosol] [Homo sapiens] [SimpleEntity:29370] ADP [cytosol]
releaseDate	2017-09-12
reviewed	[InstanceEdit:386952] Nusse, Roel, 2008-01-19
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens [Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:8915360] R-NUL-209144.4
summation	[Summation:9616760] Human APC is finally phosphorylated by Murine GSK3beta
(hasEvent)	[Pathway:209389] Wingless pathway - Inferred Events
(inferredFrom)	[Reaction:209082] Further phosphorylation of APC by SGG [Drosophila melanogaster]
(updatedInstance)	[_UpdateTracker:9779119] Update Tracker - [Reaction:209144] Human APC is finally phosphorylated by Murine GSK3beta - v66:[addSummation]
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No pathways have been reviewed or authored by Human APC is finally phosphorylated by Murine GSK3beta (209144)