Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person LACK binds to Phospho MAD/SMOX

Class:Id	Reaction:209121
_displayName	LACK binds to Phospho MAD/SMOX
_doRelease	FALSE
_timestamp	2016-07-15 23:50:04
authored	[InstanceEdit:386951] Williams, MG, 2007-03-22 16:49:12
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:205608] Williams, MG, 2007-03-27 14:11:11
figure	[Figure:870638] /figures/DrosBMPActB48.jpg
input	[DefinedSet:870624] Phospho MAD/SMOX [cytosol] [Drosophila melanogaster] [EntityWithAccessionedSequence:205962] LACK [cytosol] [Drosophila melanogaster]
literatureReference	[LiteratureReference:208366] dSmurf selectively degrades decapentaplegic-activated MAD, and its overexpression disrupts imaginal disc development [LiteratureReference:208028] The DSmurf ubiquitin-protein ligase restricts BMP signaling spatially and temporally during Drosophila embryogenesis [LiteratureReference:175938] Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase [LiteratureReference:202618] Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling
modified	[InstanceEdit:386960] Williams, MG, 2008-11-27 15:03:15 [InstanceEdit:870686] Williams, MG, 2010-06-08 [InstanceEdit:8879177] Wu, G, 2016-07-15
name	LACK binds to Phospho MAD/SMOX
output	[DefinedSet:870653] Phospho MAD/SMOX:LACK [cytosol] [Drosophila melanogaster]
precedingEvent	[Reaction:209023] Phosphorylated MAD/SMOX dissociates from SARA and the BMP/Act ligand:receptors complex [Drosophila melanogaster] [Reaction:208988] MAD is phosphorylated by Phospho TKV/SAX [Drosophila melanogaster] [Reaction:209066] MAD/SMOX is phosphorylated by Phospho BABO [Drosophila melanogaster] [Reaction:208965] MED replaces a phosphorylated MAD/SMOX and forms a heterotrimeric complex [Drosophila melanogaster] [Reaction:208966] Phosphorylated MAD/SMOX forms a homotrimeric complex [Drosophila melanogaster] [Reaction:208970] MAD/SMOX and MED transport from the nucleus to the cytosol [Drosophila melanogaster] [Reaction:870438] FAF deubiquitinates MED [Drosophila melanogaster] [Reaction:209145] Phosphorylated MAD/SMOX is ubiquitinated and dissociates from LACK [Drosophila melanogaster] [Reaction:209121] LACK binds to Phospho MAD/SMOX [Drosophila melanogaster]
species	[Species:56210] Drosophila melanogaster
stableIdentifier	[StableIdentifier:8911161] R-DME-209121.1
summation	[Summation:206503] Cytosolic phosphorylated R-Smads, MAD and SMOX, bind to HECT...
(hasEvent)	[Pathway:209418] R-Smad degradation in the cytosol [Drosophila melanogaster]
(precedingEvent)	[Reaction:209145] Phosphorylated MAD/SMOX is ubiquitinated and dissociates from LACK [Drosophila melanogaster]
[Change default viewing format]

No pathways have been reviewed or authored by LACK binds to Phospho MAD/SMOX (209121)