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Details on Person Further phosphorylation of ARM by SGG
Class:Id Reaction:209109
_displayName Further phosphorylation of ARM by SGG
_doRelease TRUE
_timestamp 2018-03-09 00:14:12
authored [InstanceEdit:386950] Williams, MG, 2006-07-26 16:49:12
catalystActivity [CatalystActivity:5263697] protein serine/threonine kinase activity of Phospho ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol]
compartment [Compartment:70101] cytosol
created [InstanceEdit:205630] Williams, MG, 2006-06-28 10:48:14
edited [InstanceEdit:5490376] Williams, MG, 2014-05-20
figure [Figure:208813] /figures/BDrosWing08.jpg
input [Complex:206805] Phospho ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] [Drosophila melanogaster] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol]
literatureReference [LiteratureReference:208219] Casein kinase I phosphorylates the Armadillo protein and induces its degradation in Drosophila [LiteratureReference:196266] Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism [LiteratureReference:196269] Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway [LiteratureReference:208299] Biochemical characterization of the Drosophila wingless signaling pathway based on RNA interference
modified [InstanceEdit:205613] Williams, MG, 2006-07-20 14:47:06 [InstanceEdit:208731] Williams, MG, 2006-09-22 14:12:19 [InstanceEdit:206331] Williams, MG, 2006-10-24 13:03:16 [InstanceEdit:350491] Williams, MG, 2008-05-19 14:10:10 [InstanceEdit:386957] Williams, MG, 2008-11-27 14:37:44 [InstanceEdit:5263696] D'Eustachio, Peter, 2014-02-14 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9024533] Matthews, Lisa, 2017-10-05 [InstanceEdit:9038602] D'Eustachio, Peter, 2018-03-09 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name Further phosphorylation of ARM by SGG
output [Complex:207028] Phospho (4 sites) ARM:Phospho (3 sites) AXN:Phospho (6 sites) APC:PP2A:CKIalpha:DCO:SGG [cytosol] [Drosophila melanogaster] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol]
precedingEvent
releaseDate 2017-09-12
reviewed [InstanceEdit:386952] Nusse, Roel, 2008-01-19
reviewStatus [ReviewStatus:9821382] five stars
species [Species:56210] Drosophila melanogaster
stableIdentifier [StableIdentifier:8893809] R-DME-209109.4
summation [Summation:206370] Phosphorylation of bound Armadillo (ARM) at Ser44, Ser48, an...
(hasEvent) [Pathway:209396] Phosphorylation of ARM [Drosophila melanogaster]
(precedingEvent) [Reaction:209102] SLMB binds to phosphorylated ARM to form the 'destruction complex' [Drosophila melanogaster] [Reaction:209120] Membrane recruitment of DSH to FZ and AXN to phosphorylated ARR [Drosophila melanogaster]
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