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Details on Person IKBA is phosphorylated by Phospho IKKB kinase

Class:IdReaction:209087
_displayNameIKBA is phosphorylated by Phospho IKKB kinase
_doReleaseTRUE
_timestamp2017-10-05 17:04:34
authored[InstanceEdit:744679] Ray, KP, 2010-05-17
catalystActivity[CatalystActivity:208866] protein serine/threonine kinase activity of p-S177,S181-IKBKB [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:205654] Williams, MG, 2007-07-12 09:20:19
edited[InstanceEdit:744685] Jupe, S, 2010-05-17
figure[Figure:208730] /figures/DrosTollImdA17.jpg
input[EntityWithAccessionedSequence:168151] NFKBIA [cytosol] [Homo sapiens]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
literatureReference[LiteratureReference:208246] IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation
[LiteratureReference:208049] Differential phosphorylation of the signal-responsive domain of I kappa B alpha and I kappa B beta by I kappa B kinases
modified[InstanceEdit:350495] Williams, MG, 2008-05-19 14:12:22
[InstanceEdit:386959] Williams, MG, 2008-11-27 14:56:57
[InstanceEdit:451601] Jupe, S, 2010-01-06
[InstanceEdit:451610] Jupe, S, 2010-01-06
[InstanceEdit:744686] Jupe, S, 2010-05-17
[InstanceEdit:772535] Jupe, S, 2010-05-21
[InstanceEdit:3211775] Jupe, S, 2013-03-08
[InstanceEdit:8879177] Wu, G, 2016-07-15
[InstanceEdit:8951416] Jupe, Steve, 2016-12-02
[InstanceEdit:9012434] Duenas, Corina, 2017-07-13
[InstanceEdit:9024533] Matthews, Lisa, 2017-10-05
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameIKBA is phosphorylated by Phospho IKKB kinase
output[EntityWithAccessionedSequence:177677] p-S32,S36-NFKBIA [cytosol] [Homo sapiens]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
releaseDate2017-09-12
reviewed[InstanceEdit:744680] Pinteaux, E, 2010-05-17
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8904437] R-HSA-209087.4
summation[Summation:206324] Human IKBA, orthologue of Drosophila Cactus (CACT), is phosp...
(hasEvent)[Pathway:9020702] Interleukin-1 signaling [Homo sapiens]
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