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Details on Person Full-length human BMP7 dimer is cleaved by Furin to form ProBMP7:BMP7 dimer complex

Class:IdReaction:209047
_displayNameFull-length human BMP7 dimer is cleaved by Furin to form ProBMP7:BMP7 dimer complex
_doReleaseFALSE
_timestamp2016-07-15 23:49:13
authored[InstanceEdit:386951] Williams, MG, 2007-03-22 16:49:12
catalystActivity[CatalystActivity:156993] serine-type endopeptidase activity of FURIN [Golgi membrane]
compartment[Compartment:20699] Golgi membrane
[Compartment:17963] Golgi lumen
created[InstanceEdit:205608] Williams, MG, 2007-03-27 14:11:11
figure[Figure:208513] /figures/DrosBMPAct010.jpg
input[Complex:206635] BMP7 full-length dimer [Golgi lumen] [Homo sapiens]
literatureReference[LiteratureReference:208041] The prodomain of BMP-7 targets the BMP-7 complex to the extracellular matrix
modified[InstanceEdit:350491] Williams, MG, 2008-05-19 14:10:10
[InstanceEdit:386957] Williams, MG, 2008-11-27 14:37:44
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:8879177] Wu, G, 2016-07-15
nameFull-length human BMP7 dimer is cleaved by Furin to form ProBMP7:BMP7 dimer complex
output[Complex:206835] ProBMP7:BMP7 dimer [Golgi lumen] [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:8888777] R-HSA-209047.1
(hasEvent)[Pathway:209460] BMP/Activin pathway - Inferred Events
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