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Details on Person MAD is phosphorylated by Phospho TKV/SAX

Class:IdReaction:208988
_displayNameMAD is phosphorylated by Phospho TKV/SAX
_doReleaseFALSE
_timestamp2016-07-15 23:50:08
authored[InstanceEdit:386951] Williams, MG, 2007-03-22 16:49:12
catalystActivity[CatalystActivity:870644] protein serine/threonine kinase activity of PUT/WIT dimer:BMP dimer:Phospho TKV/SAX dimer:MAD:SARA [early endosome membrane]
compartment[Compartment:171062] early endosome membrane
created[InstanceEdit:205608] Williams, MG, 2007-03-27 14:11:11
figure[Figure:870675] /figures/DrosBMPActB24.jpg
input[DefinedSet:870629] PUT/WIT dimer:BMP dimer:Phospho TKV/SAX dimer:MAD:SARA [plasma membrane] [Drosophila melanogaster]
[SimpleEntity:113592] ATP [cytosol]
[SimpleEntity:113592] ATP [cytosol]
literatureReference[LiteratureReference:870424] Distinct signaling of Drosophila Activin/TGF-beta family members
[LiteratureReference:208126] Drosophila dSmad2 and Atr-I transmit activin/TGFbeta signals
[LiteratureReference:208058] Interplay of signal mediators of decapentaplegic (Dpp): molecular characterization of mothers against dpp, Medea, and daughters against dpp
[LiteratureReference:208371] Different routes of bone morphogenic protein (BMP) receptor endocytosis influence BMP signaling
modified[InstanceEdit:386960] Williams, MG, 2008-11-27 15:03:15
[InstanceEdit:870686] Williams, MG, 2010-06-08
[InstanceEdit:8879177] Wu, G, 2016-07-15
nameMAD is phosphorylated by Phospho TKV/SAX
output[DefinedSet:870633] PUT/WIT dimer:BMP dimer:Phospho TKV/SAX dimer:Phospho MAD:SARA [early endosome membrane] [Drosophila melanogaster]
[SimpleEntity:29370] ADP [cytosol]
[SimpleEntity:29370] ADP [cytosol]
precedingEvent
species[Species:56210] Drosophila melanogaster
stableIdentifier[StableIdentifier:8912407] R-DME-208988.1
summation[Summation:870625] In the BMP sub-pathway, the R-Smad, MAD is phosphorylated at...
(hasEvent)[Pathway:209422] R-Smad is phosphorylated by the receptor complex [Drosophila melanogaster]
(precedingEvent)[Reaction:209023] Phosphorylated MAD/SMOX dissociates from SARA and the BMP/Act ligand:receptors complex [Drosophila melanogaster]
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