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Details on Person DPP:SCW dimer binds to TKV:SAX dimer

Class:Id	Reaction:208981
_displayName	DPP:SCW dimer binds to TKV:SAX dimer
_doRelease	FALSE
_timestamp	2016-07-15 23:48:59
authored	[InstanceEdit:386951] Williams, MG, 2007-03-22 16:49:12
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:205608] Williams, MG, 2007-03-27 14:11:11
figure	[Figure:870577] /figures/DrosBMPActB10.jpg
input	[Complex:207033] DPP:SCW [extracellular region] [Drosophila melanogaster] [Complex:206659] TKV:SAX [plasma membrane] [Drosophila melanogaster]
literatureReference	[LiteratureReference:208139] Facilitated transport of a Dpp/Scw heterodimer by Sog/Tsg leads to robust patterning of the Drosophila blastoderm embryo [LiteratureReference:208312] Spatially restricted activation of the SAX receptor by SCW modulates DPP/TKV signaling in Drosophila dorsal-ventral patterning [LiteratureReference:208265] Physical properties of Tld, Sog, Tsg and Dpp protein interactions are predicted to help create a sharp boundary in Bmp signals during dorsoventral patterning of the Drosophila embryo [LiteratureReference:202639] Structure of the ternary signaling complex of a TGF-beta superfamily member [LiteratureReference:208263] Crystal structure of the BMP-2-BRIA ectodomain complex
modified	[InstanceEdit:386957] Williams, MG, 2008-11-27 14:37:44 [InstanceEdit:870576] Williams, MG, 2010-06-08 [InstanceEdit:1043153] Wu, G, 2010-11-19 [InstanceEdit:8879177] Wu, G, 2016-07-15
name	DPP:SCW dimer binds to TKV:SAX dimer
output	[Complex:206699] DPP:SCW:TKV:SAX [plasma membrane] [Drosophila melanogaster]
precedingEvent	[Reaction:209003] Mature BMP/Act dimers transport from the trans-golgi to the extracellular space [Drosophila melanogaster] [Reaction:208990] Full-length BMP/Act dimers have their prodomains cleaved by Furin [Drosophila melanogaster] [Reaction:209029] TLD cleaves SOG and the DPP/SCW dimer complex dissociates [Drosophila melanogaster] [Reaction:209035] DPP/SCW dimers bind to SOG and TSG [Drosophila melanogaster] [Reaction:209001] Type I and Type II receptor dimers transport from the ER to the plasma membrane [Drosophila melanogaster] [Reaction:209033] Type I and Type II receptors homodimerise [Drosophila melanogaster] [Reaction:208999] Type I TKV and SAX receptors heterodimerise [Drosophila melanogaster]
species	[Species:56210] Drosophila melanogaster
stableIdentifier	[StableIdentifier:8882363] R-DME-208981.1
summation	[Summation:870578] In the BMP sub-pathway, Decapentaplegic (DPP):Screw (SCW) li...
(hasEvent)	[Pathway:209427] BMP ligand dimer binds to Type I receptor dimer at the plasma membrane [Drosophila melanogaster]
(precedingEvent)	[Reaction:208958] DPP:TKV, SCW:SAX, GBB:SAX dimer complexes and DPP:SCW:TKV:SAX complex bind to PUT dimer [Drosophila melanogaster]
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No pathways have been reviewed or authored by DPP:SCW dimer binds to TKV:SAX dimer (208981)