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Details on Person Activation of the PI3K pathway has been demonstrated downstr...

Class:IdSummation:2085647
_displayNameActivation of the PI3K pathway has been demonstrated downstr...
_timestamp2012-02-05 02:20:02
created[InstanceEdit:2085648] Rothfels, K, 2012-02-05
modified[InstanceEdit:2085649] Rothfels, K, 2012-02-05
textActivation of the PI3K pathway has been demonstrated downstream of a number of FGFR mutants (reviewed in Wesche, 2001; see for instance, Agazie, 2003; Kunii, 2008; Takeda, 2007; Chen, 2004; Demiroglu, 2001; Guasch, 2001; Byron, 2008), and is presumed to occur in a manner analogous to the wild-type receptor.
(summation)[Reaction:5655245] Activated FGFR2 mutants:p-FRS2:GRB2:GAB1:PIK3R1 binds PIK3CA [Homo sapiens]
[Reaction:5655252] Activated FGFR4 mutants:p-FRS2:GRB2:GAB1:PIK3R1 binds PIK3CA [Homo sapiens]
[Reaction:5655263] Activated FGFR1 mutants:p-FRS2:GRB2:GAB1:PIK3R1 binds PIK3CA [Homo sapiens]
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No pathways have been reviewed or authored by Activation of the PI3K pathway has been demonstrated downstr... (2085647)