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Details on Person Beta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation

Class:IdLiteratureReference:208367
_displayNameBeta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation
_timestamp2007-12-18 11:51:09
author[Person:207410] Daniels, DL
[Person:196275] Weis, William I
created[InstanceEdit:206331] Williams, MG, 2006-10-24 13:03:16
journalNat Struct Mol Biol
pages364-71
pubMedIdentifier15768032
titleBeta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activation
volume12
year2005
(literatureReference)[Complex:3299554] TLE2 tetramer [nucleoplasm] [Homo sapiens]
[Complex:3299555] TCF/LEF:TLE:HDAC1 [nucleoplasm] [Homo sapiens]
[Complex:3299557] TLE1 tetramer [nucleoplasm] [Homo sapiens]
[Complex:3299558] TLE3 tetramer [nucleoplasm] [Homo sapiens]
[Complex:3299559] TLE4 tetramer [nucleoplasm] [Homo sapiens]
[Reaction:209181] ARM displaces GRO and binds to PAN which activates transcription [Drosophila melanogaster]
[Reaction:3299569] Beta-catenin displaces TLE:HDAC1 from TCF/LEF [Homo sapiens]
[Reaction:4641229] TLE oligomerizes [Homo sapiens]
[Reaction:8944349] TLE tetramers bind TCF/LEF at WNT promoters [Homo sapiens]
[Reaction:8944352] TCF/LEF binds WNT promoters [Homo sapiens]
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