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Details on Person A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation

Class:IdLiteratureReference:208343
_displayNameA dual-kinase mechanism for Wnt co-receptor phosphorylation and activation
_timestamp2007-12-18 11:50:51
author[Person:207815] Zeng, X
[Person:68959] Tamai, K
[Person:207333] Doble, B
[Person:203638] Li, S
[Person:111125] Huang, H
[Person:207233] Habas, Raymond
[Person:207848] Okamura, H
[Person:199358] Woodgett, J
[Person:181280] He, Xi
created[InstanceEdit:205655] Williams, MG, 2006-10-24 12:52:33
journalNature
pages873-7
pubMedIdentifier16341017
titleA dual-kinase mechanism for Wnt co-receptor phosphorylation and activation
volume438
year2005
(literatureReference)[Reaction:201677] Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta [Homo sapiens]
[Reaction:201691] Phosphorylation of LRP5/6 cytoplasmic domain by CSNKI [Homo sapiens]
[Reaction:209104] Frog CKIgamma further phosphorylates Human LRP6 in the receptor complex [Homo sapiens]
[Reaction:209139] Membrane localised Human GSK3beta phosphorylates LRP6 [Homo sapiens]
[Pathway:4641262] Disassembly of the destruction complex and recruitment of AXIN to the membrane [Homo sapiens]
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