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Details on Person The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants

Class:IdLiteratureReference:208211
_displayNameThe Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants
_timestamp2007-12-18 11:49:16
author[Person:196595] Scheffzek, K
[Person:196510] Ahmadian, MR
[Person:207497] Kabsch, W
[Person:207633] Wiesmuller, L
[Person:207389] Lautwein, A
[Person:207961] Schmitz, F
[Person:165143] Wittinghofer, A
created[InstanceEdit:205618] Williams, MG, 2007-10-30 11:44:05
journalScience
pages333-8
pubMedIdentifier9219684
titleThe Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants
volume277
year1997
(literatureReference)[Reaction:209208] Human RASA1 binds to Ras:GTP complex [Homo sapiens]
[Reaction:209288] Human RASA1 dissociates from Ras:GDP complex [Homo sapiens]
[Reaction:209372] Human RASA1 hydrolyses Ras:GTP complex [Homo sapiens]
[Reaction:5658435] RAS GAPs bind RAS:GTP [Homo sapiens]
[FailedReaction:6802834] RAS GTPase mutants don't hydrolyze GTP [Homo sapiens]
[Reaction:8981355] RASA1 binds RAS:GTP [Homo sapiens]
[FailedReaction:9651280] RAS GAP mutants aren't stimulated by GAPs [Homo sapiens]
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