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Details on Person Inducible degradation of IkappaBalpha by the proteasome requires interaction with the F-box protein h-betaTrCP
| Class:Id | LiteratureReference:208176 |
| _displayName | Inducible degradation of IkappaBalpha by the proteasome requires interaction with the F-box protein h-betaTrCP |
| _timestamp | 2007-12-18 11:48:50 |
| author | [Person:207170] Kroll, M [Person:180541] Margottin, F [Person:207246] Kohl, Andreas [Person:207681] Renard, P [Person:180587] Durand, H [Person:207274] Concordet, JP [Person:207182] Bachelerie, F [Person:207446] Arenzana-Seisdedos, F [Person:180558] Benarous, Richard |
| created | [InstanceEdit:205654] Williams, MG, 2007-07-12 09:20:19 |
| journal | J Biol Chem |
| pages | 7941-5 |
| pubMedIdentifier | 10075690 |
| title | Inducible degradation of IkappaBalpha by the proteasome requires interaction with the F-box protein h-betaTrCP |
| volume | 274 |
| year | 1999 |
| (literatureReference) | [Summation:9974815] Human beta-TrCP forms part of the SCF E3 ubiquitin ligase... [BlackBoxEvent:209061] Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex [Homo sapiens] [Reaction:209125] SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex [Homo sapiens] [Reaction:9974817] SCF-Beta-TrCP complex binding to NFKB p50:p65:phospho-IKBA complex is negatively regulated by RV-A NSP1 [Homo sapiens] |
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