Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person Witthuhn, BA

Class:IdPerson:207948
_displayNameWitthuhn, BA
_timestamp2007-12-18 11:39:57
created[InstanceEdit:205673] Williams, MG, 2006-11-03 15:40:44
initialBA
surnameWitthuhn
(author)[LiteratureReference:208315] JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin
[LiteratureReference:451897] Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID
[LiteratureReference:451901] Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits
[LiteratureReference:873845] Kinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral state
[LiteratureReference:873856] Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop
[LiteratureReference:873895] Determination of the transphosphorylation sites of Jak2 kinase
[LiteratureReference:873904] Phosphorylation and activation of the DNA binding activity of purified Stat1 by the Janus protein-tyrosine kinases and the epidermal growth factor receptor
[LiteratureReference:879929] Signaling through the hematopoietic cytokine receptors
[LiteratureReference:879936] JAK2 associates with the beta c chain of the receptor for granulocyte-macrophage colony-stimulating factor, and its activation requires the membrane-proximal region
[LiteratureReference:893525] Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction
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No pathways have been reviewed or authored by Witthuhn, BA (207948)