Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person The final step in the beta-oxidation process is the thiolyti...

Class:IdSummation:2076701
_displayNameThe final step in the beta-oxidation process is the thiolyti...
_timestamp2012-01-27 16:20:17
created[InstanceEdit:2076702] Jupe, S, 2012-01-27
literatureReference[LiteratureReference:2066732] Identification of the peroxisomal beta-oxidation enzymes involved in the biosynthesis of docosahexaenoic acid
modified[InstanceEdit:2076703] Jupe, S, 2012-01-27
textThe final step in the beta-oxidation process is the thiolytic cleavage of 1-(3-oxo-6Z,9Z,12Z,15Z,18Z,21Z-tetracosahexaenoyl)-CoA to form docosahexaenoyl-CoA (DHA-CoA). This step is catalysed by both sterol carrier protein X (SCPx) and the classic 3-ketoacyl-CoA thiolase (this reaction) (Ferdinandusse et al. 2001).
(summation)[Reaction:2066788] Formation of DHA-CoA catalysed by 3-ketoacyl-CoA thiolase [Homo sapiens]
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