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Details on Person Phosphorylated WWTR1 (TAZ) and DVL interact to form a comple...

Class:IdSummation:2066297
_displayNamePhosphorylated WWTR1 (TAZ) and DVL interact to form a comple...
_timestamp2012-01-25 16:38:08
created[InstanceEdit:2066298] D'Eustachio, P, 2012-01-25
modified[InstanceEdit:2066301] D'Eustachio, P, 2012-01-25
textPhosphorylated WWTR1 (TAZ) and DVL interact to form a complex in the cytosol. Thus sequestered, DVL2 is unable to undergo phosphorylation by casein kinase, inhibiting its role in WNT signaling. WWTR1 - DLV interaction thus appears to link the Hippo and WNT signaling processes (Varelas et al. 2010). The stoichiometry of the WWTR1:DVL complex is unknown.
(summation)[Reaction:2066299] DVL2 binds phosphorylated WWTR1 (TAZ) [Homo sapiens]
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