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Details on Person Expression and characterization of recombinant human angiotensin I-converting enzyme. Evidence for a C-terminal transmembrane anchor and for a proteolytic processing of the secreted recombinant and plasma enzymes

Class:Id	LiteratureReference:2065409
_displayName	Expression and characterization of recombinant human angiotensin I-converting enzyme. Evidence for a C-terminal transmembrane anchor and for a proteolytic processing of the secreted recombinant and plasma enzymes
_timestamp	2012-01-21 21:10:57
author	[Person:213420] Wei, L [Person:2065354] Alhenc-Gelas, F [Person:2065353] Soubrier, F [Person:2065386] Michaud, A [Person:445515] Corvol, P [Person:75660] Clauser, E
created	[InstanceEdit:2065361] May, B, 2012-01-21
journal	J Biol Chem
pages	5540-6
pubMedIdentifier	1848554
title	Expression and characterization of recombinant human angiotensin I-converting enzyme. Evidence for a C-terminal transmembrane anchor and for a proteolytic processing of the secreted recombinant and plasma enzymes
volume	266
year	1991
(literatureReference)	[EntityWithAccessionedSequence:2065414] ACE(30-1232) [extracellular region] [Homo sapiens] [Reaction:2022405] ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) [Homo sapiens] [Reaction:2065355] Secreted ACE:Zn2+ hydrolyzes AGT(25-34) (Angiotensin-(1-10)) to AGT(25-32) (Angiotensin-(1-8)) [Homo sapiens] [CatalystActivityReference:9643114] metallodipeptidase activity of ACE(30-1232):Zn2+ [extracellular region] Angiotensin I-converting enzyme mutation (Trp1197Stop) causes a dramatic increase in blood ACE
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