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Details on Person The phosphorylated AP-1 transcription factor binds to its ta...

Class:IdSummation:206531
_displayNameThe phosphorylated AP-1 transcription factor binds to its ta...
_timestamp2009-12-17 11:33:17
created[InstanceEdit:205654] Williams, MG, 2007-07-12 09:20:19
modified[InstanceEdit:354301] Williams, MG, 2008-06-17 10:37:57
[InstanceEdit:450803] Williams, MG, 2009-12-17
textThe phosphorylated AP-1 transcription factor binds to its target genes and activates transcription. One of its target genes encodes the phosphatase Puckered (PUC) which acts as a negative regulator of the pathway as part of a negative feedback loop.

In the eye, another transcriptional target, arising from the Frizzled (FZ):Dishevelled (DSH) complex activation in R3 cells, is for the Notch (N) receptor ligand Delta (DL). This will subsequently bind to its receptor N in the neighbouring R4 cell.
(summation)[Reaction:209358] Phosphorylated AP-1, Phospho JRA:Phospho KAY binds to a target gene and activates transcription [Drosophila melanogaster]
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