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Details on Person Effect of transmembrane and kinase domain mutations on fibroblast growth factor receptor 3 chimera signaling in PC12 cells. A model for the control of receptor tyrosine kinase activation

Class:IdLiteratureReference:2054036
_displayNameEffect of transmembrane and kinase domain mutations on fibroblast growth factor receptor 3 chimera signaling in PC12 cells. A model for the control of receptor tyrosine kinase activation
_timestamp2012-01-12 21:58:38
author[Person:1295574] Raffioni, S
[Person:2054030] Zhu, YZ
[Person:1295552] Bradshaw, RA
[Person:1295579] Thompson, LM
created[InstanceEdit:2054035] Rothfels, K, 2012-01-12
journalJ Biol Chem
pages35250-9
pubMedIdentifier9857065
titleEffect of transmembrane and kinase domain mutations on fibroblast growth factor receptor 3 chimera signaling in PC12 cells. A model for the control of receptor tyrosine kinase activation
volume273
year1998
(literatureReference)[Reaction:2023456] Dimerization of FGFR1 point mutants with enhanced kinase activity [Homo sapiens]
[Reaction:2023460] Autocatalytic phosphorylation of FGFR1 mutants with enhanced kinase activity [Homo sapiens]
[Reaction:2033479] Dimerization of FGFR2 point mutants with enhanced kinase activity [Homo sapiens]
[Reaction:2033490] Autocatalytic phosphorylation of FGFR2 point mutants with enhanced kinase activity [Homo sapiens]
[Reaction:5655233] Activated FGFR2 mutants:p-FRS2 binds GRB2-SOS1 [Homo sapiens]
[Reaction:5655241] Activated FGFR2 mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange [Homo sapiens]
[Reaction:5655266] Activated FGFR1 mutants:p-FRS2 binds GRB2-SOS1 [Homo sapiens]
[Reaction:5655268] Activated FGFR2 mutants phosphorylate FRS2 [Homo sapiens]
[Reaction:5655270] Activated FGFR3 point, translocation and fusion mutants phosphorylate FRS2 [Homo sapiens]
[Reaction:5655277] Activated FGFR3 point, translocation and fusion mutants:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange [Homo sapiens]
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