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Details on Person Interaction of Src family kinases with p-KIT

Class:Id	Reaction:205205
_displayName	Interaction of Src family kinases with p-KIT
_doRelease	TRUE
_timestamp	2011-09-09 09:08:33
authored	[InstanceEdit:1433337] Garapati, P V, 2011-07-11
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:205198] Garapati, P V, 2007-12-10 09:55:47
edited	[InstanceEdit:1433337] Garapati, P V, 2011-07-11
inferredFrom	[Reaction:1433273] Interaction of Src kinases with c-Kit [Mus musculus]
input	[DefinedSet:211064] Src family tyrosine kinases (SFKs) [cytosol] [Homo sapiens] [Complex:205310] p-7Y-KIT:sSCF dimer:p-7Y-KIT [plasma membrane] [Homo sapiens]
modified	[InstanceEdit:1433337] Garapati, P V, 2011-07-11 [InstanceEdit:1470085] Garapati, P V, 2011-08-02 [InstanceEdit:1500885] Garapati, P V, 2011-08-22 [InstanceEdit:1524178] Garapati, P V, 2011-08-24 [InstanceEdit:1538125] Garapati, P V, 2011-08-26 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Interaction of Src family kinases with p-KIT
output	[Complex:205271] SFKs:p-KIT complex [plasma membrane] [Homo sapiens]
precedingEvent	[Reaction:205289] Autophosphorylation of KIT [Homo sapiens] [Reaction:205231] Dimerization of KIT upon SCF binding [Homo sapiens]
releaseDate	2011-09-20
reviewed	[InstanceEdit:1500883] R�nnstrand, Lars, 2011-08-22
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:1591467] R-HSA-205205.2
summation	[Summation:1433308] Binding of SCF to KIT induces the activation and rapid incre...
(hasEvent)	[Pathway:1433557] Signaling by SCF-KIT [Homo sapiens]
(normalReaction)	[Reaction:9670414] KIT mutants bind SFKs [Homo sapiens]
(precedingEvent)	[Reaction:205238] SHP2 interacts with p-KIT [Homo sapiens] [Reaction:1433451] JAK2 binds to p-KIT [Homo sapiens] [Reaction:1433542] Phosphorylation and activation of VAV1 [Homo sapiens] [Reaction:1472121] Phosphorylation of p-KIT on Y900 by Src kinases [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9777328] Update Tracker - [Reaction:205205] Interaction of Src family kinases with p-KIT - v72:[modifyText] [_UpdateTracker:9788630] Update Tracker - [Reaction:205205] Interaction of Src family kinases with p-KIT - v41:[modifyText]
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No pathways have been reviewed or authored by Interaction of Src family kinases with p-KIT (205205)