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Details on Person Interaction of Tie2 and Grb2

Class:IdReaction:204871
_displayNameInteraction of Tie2 and Grb2
_doReleaseTRUE
_timestamp2012-11-21 23:16:38
authored[InstanceEdit:215562] Garapati, P V, de Bono, B, 2008-03-05 10:26:56
compartment[Compartment:876] plasma membrane
[Compartment:70101] cytosol
created[InstanceEdit:204777] Garapati, P V, 2007-12-03 09:53:12
input[EntityWithAccessionedSequence:74686] GRB2-1 [cytosol] [Homo sapiens]
[Complex:204783] ANGPT1:p-5Y,S119-TEK [plasma membrane] [Homo sapiens]
literatureReference[LiteratureReference:204811] Tek/Tie2 signaling: new and old partners
[LiteratureReference:204835] GRB2 and SH-PTP2: potentially important endothelial signaling molecules downstream of the TEK/TIE2 receptor tyrosine kinase
[LiteratureReference:204862] Identification of Tek/Tie2 binding partners. Binding to a multifunctional docking site mediates cell survival and migration.
modified[InstanceEdit:204875] Garapati, P V, 2007-12-03 11:03:52
[InstanceEdit:210879] Garapati, P V, 2008-01-17 14:13:36
[InstanceEdit:210971] Garapati, P V, 2008-01-18 15:29:04
[InstanceEdit:210989] Garapati, P V, 2008-01-22 15:06:28
[InstanceEdit:211549] de Bono, B, 2008-02-06 09:45:07
[InstanceEdit:213345] Gopinathrao, G, 2008-02-25 21:36:16
[InstanceEdit:214831] Garapati, P V, 2008-02-26 12:21:18
[InstanceEdit:214882] Garapati, P V, 2008-02-26 12:32:59
[InstanceEdit:215251] Gopinathrao, G, 2008-02-27 21:37:06
[InstanceEdit:215563] Garapati, P V, 2008-03-05 10:30:39
[InstanceEdit:215569] Garapati, P V, 2008-03-05 12:10:33
[InstanceEdit:391192] Garapati, P V, 2009-02-13 12:51:21
[InstanceEdit:2648974] D'Eustachio, P, 2012-11-21
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameInteraction of Tie2 and Grb2
output[Complex:204865] Grb2 bound to Tie2 [plasma membrane] [Homo sapiens]
precedingEvent
releaseDate2008-03-12
reviewed[InstanceEdit:214481] Trowsdale, J, 2008-02-26 12:02:59
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359632] R-HSA-204871.2
summation[Summation:210975] Tie2/Tek provide mitogenic signals to endothelial cells by p...
(hasEvent)[Pathway:210993] Tie2 Signaling [Homo sapiens]
(precedingEvent)[Reaction:210974] Interaction of SOS-1 to Tie2 bound Grb2 [Homo sapiens]
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No pathways have been reviewed or authored by Interaction of Tie2 and Grb2 (204871)