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Details on Person Cytosolic deoxyhypusine synthase (DHPS) tetramer catalyzes t...
| Class:Id | Summation:204653 |
|---|---|
| _displayName | Cytosolic deoxyhypusine synthase (DHPS) tetramer catalyzes t... |
| _timestamp | 2016-10-17 17:55:06 |
| created | [InstanceEdit:204657] D'Eustachio, P, 2007-11-28 23:36:29 |
| modified | [InstanceEdit:8942445] D'Eustachio, Peter, 2016-10-14 [InstanceEdit:8942537] D'Eustachio, Peter, 2016-10-17 |
| text | Cytosolic deoxyhypusine synthase (DHPS) tetramer catalyzes the reaction of the deoxyhypusine (Dhp) residue in EIF5A protein (Dhp-K50-EIF5A) with 1,3 diaminopropane, NADH and H+ to form EIF5A, spermidine (SPM), and NAD+ (Park et al. 2003; Park 2006). While this reaction is readily observed in vitro, it is probably minimized by the rapid, irreversible conversion of EIF5A Dhp residues to hypusine. |
| (summation) | [Reaction:204617] DHPS tetramer synthesizes EIF5A and spermidine from Dhp-K50-EIF5A [Homo sapiens] |
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No pathways have been reviewed or authored by Cytosolic deoxyhypusine synthase (DHPS) tetramer catalyzes t... (204653)
