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Details on Person Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA

Class:IdReaction:2046092
_displayNameDesaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA
_doReleaseTRUE
_timestamp2012-05-31 09:45:17
authored[InstanceEdit:2046103] Garapati, P V, 2012-01-11
catalystActivity[CatalystActivity:2046077] omega-6 fatty acid desaturase activity of FADS1 [endoplasmic reticulum membrane]
compartment[Compartment:17957] endoplasmic reticulum lumen
[Compartment:12045] endoplasmic reticulum membrane
created[InstanceEdit:2046086] Garapati, P V, 2012-01-11
edited[InstanceEdit:2046103] Garapati, P V, 2012-01-11
input[SimpleEntity:2046045] DGL-CoA [endoplasmic reticulum lumen]
[SimpleEntity:113534] O2 [endoplasmic reticulum lumen]
[SimpleEntity:194697] NADH [endoplasmic reticulum lumen]
[SimpleEntity:194697] NADH [endoplasmic reticulum lumen]
isChimericFALSE
literatureReference[LiteratureReference:2045977] Cloning, expression, and fatty acid regulation of the human delta-5 desaturase
[LiteratureReference:2046018] cDNA cloning and characterization of human Delta5-desaturase involved in the biosynthesis of arachidonic acid
modified[InstanceEdit:2066793] Garapati, P V, 2012-01-25
[InstanceEdit:2108997] Garapati, P V, 2012-02-13
[InstanceEdit:2152409] Garapati, P V, 2012-02-27
[InstanceEdit:2203420] Garapati, P V, 2012-04-20
[InstanceEdit:2248841] Garapati, P V, 2012-05-14
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameDesaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA
output[SimpleEntity:2046053] AA-CoA [endoplasmic reticulum lumen]
[SimpleEntity:113519] H2O [endoplasmic reticulum lumen]
[SimpleEntity:113519] H2O [endoplasmic reticulum lumen]
[SimpleEntity:194653] NAD+ [endoplasmic reticulum lumen]
[SimpleEntity:194653] NAD+ [endoplasmic reticulum lumen]
precedingEvent
releaseDate2012-06-12
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:2294964] R-HSA-2046092.2
summation[Summation:2045935] DGL-CoA (8,11,14-eicosatrienoyl-CoA) undergoes desaturation ...
(hasEvent)[Pathway:2046105] Linoleic acid (LA) metabolism [Homo sapiens]
(precedingEvent)[Reaction:2046083] Elongation of arachidonyl-CoA to docosatetraenoyl-CoA [Homo sapiens]
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