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Details on Person Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA

Class:IdReaction:2046089
_displayNameDesaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA
_doReleaseTRUE
_timestamp2012-05-31 09:50:31
authored[InstanceEdit:2046103] Garapati, P V, 2012-01-11
catalystActivity[CatalystActivity:2046077] omega-6 fatty acid desaturase activity of FADS1 [endoplasmic reticulum membrane]
compartment[Compartment:17957] endoplasmic reticulum lumen
[Compartment:12045] endoplasmic reticulum membrane
created[InstanceEdit:2046086] Garapati, P V, 2012-01-11
edited[InstanceEdit:2046103] Garapati, P V, 2012-01-11
input[SimpleEntity:2046051] ETA-CoA [endoplasmic reticulum lumen]
[SimpleEntity:113534] O2 [endoplasmic reticulum lumen]
[SimpleEntity:194697] NADH [endoplasmic reticulum lumen]
[SimpleEntity:194697] NADH [endoplasmic reticulum lumen]
isChimericFALSE
literatureReference[LiteratureReference:2045977] Cloning, expression, and fatty acid regulation of the human delta-5 desaturase
[LiteratureReference:2046002] Comparison of the metabolism of alpha-linolenic acid and its delta 6 desaturation product, stearidonic acid, in cultured NIH-3T3 cells
modified[InstanceEdit:2066793] Garapati, P V, 2012-01-25
[InstanceEdit:2108997] Garapati, P V, 2012-02-13
[InstanceEdit:2152409] Garapati, P V, 2012-02-27
[InstanceEdit:2203420] Garapati, P V, 2012-04-20
[InstanceEdit:2248841] Garapati, P V, 2012-05-14
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameDesaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA
output[SimpleEntity:2046059] EPA-CoA [endoplasmic reticulum lumen]
[SimpleEntity:113519] H2O [endoplasmic reticulum lumen]
[SimpleEntity:113519] H2O [endoplasmic reticulum lumen]
[SimpleEntity:194653] NAD+ [endoplasmic reticulum lumen]
[SimpleEntity:194653] NAD+ [endoplasmic reticulum lumen]
precedingEvent
releaseDate2012-06-12
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:2295159] R-HSA-2046089.2
summation[Summation:2045928] Eicosatetraenoyl-CoA (ETA-CoA) is desaturated by an addition...
(hasEvent)[Pathway:2046106] alpha-linolenic acid (ALA) metabolism [Homo sapiens]
(precedingEvent)[Reaction:2046100] Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA [Homo sapiens]
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