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Details on Person Translocation of tetracosahexaenoyl-CoA to peroxisomes

Class:Id	Reaction:2046087
_displayName	Translocation of tetracosahexaenoyl-CoA to peroxisomes
_doRelease	TRUE
_timestamp	2012-05-31 09:38:53
authored	[InstanceEdit:2046103] Garapati, P V, 2012-01-11
catalystActivity	[CatalystActivity:2046078] long-chain fatty acid transmembrane transporter activity of ABCD1 [peroxisomal membrane]
catalystActivityReference	[CatalystActivityReference:9643294] long-chain fatty acid transporter activity of ABCD1 [peroxisomal membrane] Peroxisomal straight-chain Acyl-CoA oxidase and D-bifunctional protein are essential for the retroconversion step in docosahexaenoic acid synthesis
compartment	[Compartment:17957] endoplasmic reticulum lumen [Compartment:12045] endoplasmic reticulum membrane [Compartment:17947] peroxisomal membrane [Compartment:17951] peroxisomal matrix
created	[InstanceEdit:2046086] Garapati, P V, 2012-01-11
edited	[InstanceEdit:2046103] Garapati, P V, 2012-01-11
input	[SimpleEntity:211579] ATP [endoplasmic reticulum membrane] [SimpleEntity:2046054] THA-CoA [endoplasmic reticulum lumen]
isChimeric	FALSE
literatureReference	[LiteratureReference:2066757] Docosahexaenoic acid synthesis in human skin fibroblasts involves peroxisomal retroconversion of tetracosahexaenoic acid [LiteratureReference:2046037] Peroxisomal straight-chain Acyl-CoA oxidase and D-bifunctional protein are essential for the retroconversion step in docosahexaenoic acid synthesis [LiteratureReference:2045971] Studies on the metabolic fate of n-3 polyunsaturated fatty acids
modified	[InstanceEdit:2066793] Garapati, P V, 2012-01-25 [InstanceEdit:2108997] Garapati, P V, 2012-02-13 [InstanceEdit:2152409] Garapati, P V, 2012-02-27 [InstanceEdit:2203420] Garapati, P V, 2012-04-20 [InstanceEdit:2248841] Garapati, P V, 2012-05-14 [InstanceEdit:2250302] Garapati, P V, 2012-05-15 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Translocation of tetracosahexaenoyl-CoA to peroxisomes
output	[SimpleEntity:211606] ADP [endoplasmic reticulum membrane] [SimpleEntity:426639] PI [endoplasmic reticulum membrane] [SimpleEntity:2046047] THA-CoA [peroxisomal matrix]
precedingEvent	[Reaction:2046099] Desaturation of tetracosapentaenoyl-CoA to tetracosahexaenoyl-CoA [Homo sapiens] [Reaction:2046090] Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA [Homo sapiens]
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2294699] R-HSA-2046087.3
summation	[Summation:2045939] The 24-carbon tetracosahexaenoyl-CoA (6,9,12,15,18,21-24:6(n...
(hasEvent)	[Pathway:2046106] alpha-linolenic acid (ALA) metabolism [Homo sapiens]
(precedingEvent)	[Reaction:2066787] Oxidation of tetracosapentaenoyl-CoA to delta2-tetracosaheptaenoyl-CoA [Homo sapiens]
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