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Details on Person Elongation of arachidonyl-CoA to docosatetraenoyl-CoA

Class:Id	Reaction:2046083
_displayName	Elongation of arachidonyl-CoA to docosatetraenoyl-CoA
_doRelease	TRUE
_timestamp	2012-05-31 09:46:18
authored	[InstanceEdit:2046103] Garapati, P V, 2012-01-11
catalystActivity	[CatalystActivity:2046081] fatty acid elongase activity of ELOVL5/ELOVL2 [endoplasmic reticulum membrane]
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:2046086] Garapati, P V, 2012-01-11
edited	[InstanceEdit:2046103] Garapati, P V, 2012-01-11
input	[SimpleEntity:2046053] AA-CoA [endoplasmic reticulum lumen] [SimpleEntity:2046066] Malonyl-CoA [endoplasmic reticulum lumen] [SimpleEntity:113601] NADPH [endoplasmic reticulum lumen] [SimpleEntity:113601] NADPH [endoplasmic reticulum lumen]
isChimeric	FALSE
literatureReference	[LiteratureReference:548753] Cloning of a human cDNA encoding a novel enzyme involved in the elongation of long-chain polyunsaturated fatty acids
modified	[InstanceEdit:2108997] Garapati, P V, 2012-02-13 [InstanceEdit:2152409] Garapati, P V, 2012-02-27 [InstanceEdit:2203420] Garapati, P V, 2012-04-20 [InstanceEdit:2248841] Garapati, P V, 2012-05-14 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Elongation of arachidonyl-CoA to docosatetraenoyl-CoA arachidonoyl-CoA + malonyl-CoA => 3-oxo-(7,10,13,16)-docosatetraenoyl-CoA + CO2 + CoASH [ELOVL5]
output	[SimpleEntity:2046060] DTA-CoA [endoplasmic reticulum lumen] [SimpleEntity:159751] CO2 [endoplasmic reticulum lumen] [SimpleEntity:162743] CoA-SH [endoplasmic reticulum lumen] [SimpleEntity:113519] H2O [endoplasmic reticulum lumen]
precedingEvent	[Reaction:2046092] Desaturation of dihomo-gamma-lenolenoyl-CoA to arachidonoyl-CoA [Homo sapiens] [Reaction:2046094] Elongation of gamma-lenolenoyl-CoA to dihomo-gamma-lenolenoyl-CoA [Homo sapiens]
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2294999] R-HSA-2046083.2
summation	[Summation:2045934] Arachidonyl-CoA undergoes a two-carbon chain elongation on t...
(hasEvent)	[Pathway:2046105] Linoleic acid (LA) metabolism [Homo sapiens]
(precedingEvent)	[Reaction:2046095] Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA [Homo sapiens]
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