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Details on Person Eicosatetraenoyl-CoA (ETA-CoA) is desaturated by an addition...
| Class:Id | Summation:2045928 |
|---|---|
| _displayName | Eicosatetraenoyl-CoA (ETA-CoA) is desaturated by an addition... |
| _timestamp | 2012-01-27 16:19:36 |
| created | [InstanceEdit:2045929] Garapati, P V, 2012-01-11 |
| literatureReference | [LiteratureReference:2066722] Long-chain n-3 polyunsaturated fatty acids: new insights into mechanisms relating to inflammation and coronary heart disease |
| modified | [InstanceEdit:2066719] Garapati, P V, 2012-01-25 [InstanceEdit:2076702] Jupe, S, 2012-01-27 |
| text | Eicosatetraenoyl-CoA (ETA-CoA) is desaturated by an additional carbon-carbon bond to form 5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl-CoA (EPA-CoA, 5,8,11,14,17-20:5(n-3)). Delta-5-desaturase is required for this conversion. EPA-CoA has health benefits due to its anti-inflammatory actions. It is a precursor for the anti-inflammatory series-3 prostaglandins (PG), the series-5 leukotrienes (LT) and the series-3 thromboxanes (TA), which are anti-atherogenic and anti-thrombogenic (Ross et al. 2009). |
| (summation) | [Reaction:2046089] Desaturation of eicosatetraenoyl-CoA to eicosapentaenoyl-CoA [Homo sapiens] |
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No pathways have been reviewed or authored by Eicosatetraenoyl-CoA (ETA-CoA) is desaturated by an addition... (2045928)
