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Details on Person Interaction of Csk with PAG

Class:IdReaction:203774
_displayNameInteraction of Csk with PAG
_doReleaseTRUE
_timestamp2008-06-20 09:40:51
authored[InstanceEdit:211006] Rudd, C.E., de Bono, B, Garapati, P V, 2008-01-24 15:53:10
compartment[Compartment:70101] cytosol
[Compartment:876] plasma membrane
created[InstanceEdit:203775] Garapati, P V, 2007-11-16 10:35:36
input[EntityWithAccessionedSequence:180494] p-Y317-PAG1 [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:203776] CSK [cytosol] [Homo sapiens]
literatureReference[LiteratureReference:204096] Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation
[LiteratureReference:204109] The activation of Csk by CD4 interferes with TCR-mediated activatory signaling
modified[InstanceEdit:203950] Gopinathrao, G, 2007-11-20 16:27:22
[InstanceEdit:204098] de Bono, B, 2007-11-25 09:13:59
[InstanceEdit:204115] de Bono, B, 2007-11-25 09:35:47
[InstanceEdit:212474] Garapati, P V, 2008-02-12 09:52:01
[InstanceEdit:213345] Gopinathrao, G, 2008-02-25 21:36:16
[InstanceEdit:213439] Garapati, P V, 2008-02-26 11:34:22
[InstanceEdit:214480] Garapati, P V, 2008-02-26 12:04:24
[InstanceEdit:215251] Gopinathrao, G, 2008-02-27 21:37:06
[InstanceEdit:1043153] Wu, G, 2010-11-19
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameInteraction of Csk with PAG
output[Complex:202297] Csk:p-PAG [plasma membrane] [Homo sapiens]
releaseDate2008-03-12
reviewed[InstanceEdit:214481] Trowsdale, J, 2008-02-26 12:02:59
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359388] R-HSA-203774.2
summation[Summation:203773] Csk is a tyrosine kinase that phosphorylates the negative re...
(hasEvent)[Pathway:202427] Phosphorylation of CD3 and TCR zeta chains [Homo sapiens]
(precedingEvent)[Reaction:202233] Inactivation of Lck by Csk [Homo sapiens]
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No pathways have been reviewed or authored by Interaction of Csk with PAG (203774)