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Details on Person N-myristoylation of eNOS

Class:IdReaction:203611
_displayNameN-myristoylation of eNOS
_doReleaseTRUE
_timestamp2024-08-02 15:44:07
authored[InstanceEdit:202104] Hemish, J, 2007-10-19 18:00:42
catalystActivity[CatalystActivity:2534052] glycylpeptide N-tetradecanoyltransferase activity of NMT1/2 [cytosol]
catalystActivityReference[CatalystActivityReference:9911165] glycylpeptide N-tetradecanoyltransferase activity of NMT1/2 [cytosol] Protein N-myristoylation
compartment[Compartment:70101] cytosol
created[InstanceEdit:202104] Hemish, J, 2007-10-19 18:00:42
crossReference[DatabaseIdentifier:9911150] RHEA:15522
inferredFrom
input[EntityWithAccessionedSequence:202114] NOS3 [cytosol] [Homo sapiens]
[SimpleEntity:184174] MYS-CoA [cytosol]
internalReviewed[InstanceEdit:9911325] D'Eustachio, Peter, 2024-05-28
literatureReference[LiteratureReference:9911122] Protein N-myristoylation
[LiteratureReference:203714] Identification of covalently bound amino-terminal myristic acid in endothelial nitric oxide synthase
modified[InstanceEdit:204294] Gopinathrao, G, 2007-11-27 21:50:36
[InstanceEdit:212984] Gopinathrao, G, 2008-02-16 13:08:05
[InstanceEdit:213341] Gopinathrao, G, 2008-02-25 19:53:36
[InstanceEdit:215251] Gopinathrao, G, 2008-02-27 21:37:06
[InstanceEdit:215281] Gopinathrao, G, 2008-02-28 04:43:00
[InstanceEdit:215295] Gopinathrao, G, 2008-02-28 05:37:31
[InstanceEdit:215431] Gopinathrao, G, 2008-02-28 15:47:21
[InstanceEdit:215471] Gopinathrao, G, 2008-02-28 17:53:21
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9911167] D'Eustachio, Peter, 2024-05-24
[InstanceEdit:9911326] D'Eustachio, Peter, 2024-05-28
[InstanceEdit:9917336] D'Eustachio, Peter, 2024-08-02
nameN-myristoylation of eNOS
N-terminal glycyl-(protein) + tetradecanoyl-CoA => CoA + H(+) + N-tetradecanoylglycyl-(protein)
output[EntityWithAccessionedSequence:203687] MyrG-NOS3 [cytosol] [Homo sapiens]
[SimpleEntity:70106] H+ [cytosol]
[SimpleEntity:76194] CoA-SH [cytosol]
previousReviewStatus[ReviewStatus:9821385] four stars
releaseDate2008-03-12
reviewed[InstanceEdit:215470] Enikolopov, G, 2008-02-28 17:52:44
[InstanceEdit:9917333] Hill, David P, 2024-08-02
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:359276] R-HSA-203611.3
structureModified[InstanceEdit:9911167] D'Eustachio, Peter, 2024-05-24
summation[Summation:203657] The enzymes glycylpeptide N-tetradecanoyltransferase 1 and 2...
(hasEvent)[Pathway:203615] eNOS activation [Homo sapiens]
(precedingEvent)[Reaction:203567] Palmitoylation of eNOS [Homo sapiens]
(updatedInstance)[_UpdateTracker:9919491] Update Tracker - [Reaction:203611] N-myristoylation of eNOS - v90:[modifyText, removeCatalystActivity, removeLiteratureReference, removeOutput]
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