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Details on Person Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice

Class:IdLiteratureReference:2033241
_displayNameAntibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice
_timestamp2012-01-09 03:51:05
author[Person:2033159] Qing, J
[Person:2033093] Du, X
[Person:2033074] Chen, Y
[Person:2033073] Chan, P
[Person:186698] Li, H
[Person:2033223] Wu, Ping
[Person:2033139] Marsters, S
[Person:2033182] Stawicki, S
[Person:2033193] Tien, J
[Person:2033196] Totpal, K
[Person:2033173] Ross, S
[Person:2033187] Stinson, S
[Person:2033091] Dornan, D
[Person:2033099] French, D
[Person:2033214] Wang, QR
[Person:2033184] Stephan, JP
[Person:2033225] Wu, Y
[Person:2033220] Wiesmann, C
[Person:1250148] Ashkenazi, A
created[InstanceEdit:2033250] Rothfels, K, 2012-01-09
journalJ Clin Invest
pages1216-29
pubMedIdentifier19381019
titleAntibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice
volume119
year2009
(literatureReference)[Pathway:2033515] t(4;14) translocations of FGFR3 [Homo sapiens]
[Reaction:2038386] Dimerization of FGFR3 t(4;14) translocation mutants [Homo sapiens]
[Reaction:2038387] Autocatalytic phosphorylation of FGFR3 t(4;14) translocation mutants [Homo sapiens]
[Reaction:2077420] FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors [Homo sapiens]
[Reaction:5655262] Activated FGFR3 point, translocation and fusion mutants bind FRS2 [Homo sapiens]
[Reaction:5655268] Activated FGFR2 mutants phosphorylate FRS2 [Homo sapiens]
[Reaction:5655269] Activated FGFR1 mutants bind FRS2 [Homo sapiens]
[Reaction:5655270] Activated FGFR3 point, translocation and fusion mutants phosphorylate FRS2 [Homo sapiens]
[Reaction:5655278] Activated FGFR1 mutants phosphorylate FRS2 [Homo sapiens]
[Reaction:5655284] Activated FGFR4 mutants phosphorylate FRS2 [Homo sapiens]
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