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Details on Person Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice
| Class:Id | LiteratureReference:2033241 |
| _displayName | Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice |
| _timestamp | 2012-01-09 03:51:05 |
| author | [Person:2033159] Qing, J [Person:2033093] Du, X [Person:2033074] Chen, Y [Person:2033073] Chan, P [Person:186698] Li, H [Person:2033223] Wu, Ping [Person:2033139] Marsters, S [Person:2033182] Stawicki, S [Person:2033193] Tien, J [Person:2033196] Totpal, K [Person:2033173] Ross, S [Person:2033187] Stinson, S [Person:2033091] Dornan, D [Person:2033099] French, D [Person:2033214] Wang, QR [Person:2033184] Stephan, JP [Person:2033225] Wu, Y [Person:2033220] Wiesmann, C [Person:1250148] Ashkenazi, A |
| created | [InstanceEdit:2033250] Rothfels, K, 2012-01-09 |
| journal | J Clin Invest |
| pages | 1216-29 |
| pubMedIdentifier | 19381019 |
| title | Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice |
| volume | 119 |
| year | 2009 |
| (literatureReference) | [Pathway:2033515] t(4;14) translocations of FGFR3 [Homo sapiens] [Reaction:2038386] Dimerization of FGFR3 t(4;14) translocation mutants [Homo sapiens] [Reaction:2038387] Autocatalytic phosphorylation of FGFR3 t(4;14) translocation mutants [Homo sapiens] [Reaction:2077420] FGFR3 mutants bind and are inactivated by tyrosine kinase inhibitors [Homo sapiens] [Reaction:5655262] Activated FGFR3 point, translocation and fusion mutants bind FRS2 [Homo sapiens] [Reaction:5655268] Activated FGFR2 mutants phosphorylate FRS2 [Homo sapiens] [Reaction:5655269] Activated FGFR1 mutants bind FRS2 [Homo sapiens] [Reaction:5655270] Activated FGFR3 point, translocation and fusion mutants phosphorylate FRS2 [Homo sapiens] [Reaction:5655278] Activated FGFR1 mutants phosphorylate FRS2 [Homo sapiens] [Reaction:5655284] Activated FGFR4 mutants phosphorylate FRS2 [Homo sapiens] |
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No pathways have been reviewed or authored by Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice (2033241)