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Details on Person p-6Y-FGFR3b G697C [plasma membrane]

Class:Id	EntityWithAccessionedSequence:2032969
_displayName	p-6Y-FGFR3b G697C [plasma membrane]
_timestamp	2014-11-20 17:32:17
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:2032968] Rothfels, K, 2012-01-08
crossReference	[DatabaseIdentifier:2032970] COSMIC:COSV53390947
disease	[Disease:1248679] head and neck squamous cell carcinoma [Disease:1500689] cancer
endCoordinate	808
hasModifiedResidue	[ModifiedResidue:190954] O4'-phospho-L-tyrosine at 579 [ModifiedResidue:190955] O4'-phospho-L-tyrosine at 649 [ModifiedResidue:190386] O4'-phospho-L-tyrosine at 650 [ModifiedResidue:190953] O4'-phospho-L-tyrosine at 726 [ModifiedResidue:190952] O4'-phospho-L-tyrosine at 762 [ModifiedResidue:1307902] O4'-phospho-L-tyrosine at 772 [ReplacedResidue:2018742] glycine 697 replaced with L-cysteine
literatureReference	[LiteratureReference:2032920] Constitutive activating mutation of the FGFR3b in oral squamous cell carcinomas
modified	[InstanceEdit:2105031] Rothfels, K, 2012-02-09 [InstanceEdit:3450990] Jupe, S, 2013-05-16 [InstanceEdit:3499324] Jupe, S, 2013-05-17 [InstanceEdit:3622482] Rothfels, K, 2013-05-24 [InstanceEdit:5649603] Rothfels, Karen, 2014-11-20
name	p-6Y-FGFR3b G697C p-6XY-FGFR3-2 G697C
referenceEntity	[ReferenceIsoform:147316] UniProt:P22607-2 FGFR3 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2297623] R-HSA-2032969.1
startCoordinate	23
summation	[Summation:2032971] Note that residue G697C is numbered according to the FGFR3c ...
(hasComponent)	[Complex:2033340] Activated FGFR3b G967C [plasma membrane] [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9881455] Update Tracker - [EntityWithAccessionedSequence:2032969] p-6Y-FGFR3b G697C [plasma membrane] - v45:[addName] [_UpdateTracker:9891366] Update Tracker - [EntityWithAccessionedSequence:2032969] p-6Y-FGFR3b G697C [plasma membrane] - v52:[modifyName]
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No pathways have been reviewed or authored by p-6Y-FGFR3b G697C [plasma membrane] (2032969)