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Details on Person Profound ligand-independent kinase activation of fibroblast growth factor receptor 3 by the activation loop mutation responsible for a lethal skeletal dysplasia, thanatophoric dysplasia type II

Class:IdLiteratureReference:2032934
_displayNameProfound ligand-independent kinase activation of fibroblast growth factor receptor 3 by the activation loop mutation responsible for a lethal skeletal dysplasia, thanatophoric dysplasia type II
_timestamp2012-01-08 03:52:13
author[Person:1629818] Webster, MK
[Person:2018763] d'Avis, PY
[Person:190961] Robertson, SC
[Person:190965] Donoghue, DJ
created[InstanceEdit:2032935] Rothfels, K, 2012-01-08
journalMol Cell Biol
pages4081-7
pubMedIdentifier8754806
titleProfound ligand-independent kinase activation of fibroblast growth factor receptor 3 by the activation loop mutation responsible for a lethal skeletal dysplasia, thanatophoric dysplasia type II
volume16
year1996
(literatureReference)[Pathway:1839130] Signaling by activated point mutants of FGFR3 [Homo sapiens]
[Reaction:2033476] Dimerization of FGFR3 point mutants with enhanced kinase activity [Homo sapiens]
[Reaction:2033485] Autocatalytic phosphorylation of FGFR3 point mutants with enhanced kinase activity [Homo sapiens]
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