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Details on Person Sel1l negatively regulates Pre-Notch exit from endoplasmic reticulum

Class:Id	Reaction:2032750
_displayName	Sel1l negatively regulates Pre-Notch exit from endoplasmic reticulum
_doRelease	TRUE
_timestamp	2016-11-03 15:45:12
authored	[InstanceEdit:2121208] Egan, SE, Orlic-Milacic, M, 2011-11-14
compartment	[Compartment:12045] endoplasmic reticulum membrane [Compartment:20699] Golgi membrane
created	[InstanceEdit:2032753] Orlic-Milacic, M, 2012-01-06
edited	[InstanceEdit:2106576] Orlic-Milacic, M, 2012-02-10 [InstanceEdit:2098673] D'Eustachio, P, 2012-02-06
input	[CandidateSet:2023170] Glc,Fuc-Pre-Notch [endoplasmic reticulum membrane] [Mus musculus]
isChimeric	FALSE
literatureReference	[LiteratureReference:2032754] SEL1L deficiency impairs growth and differentiation of pancreatic epithelial cells [LiteratureReference:2032749] Suppressors of a lin-12 hypomorph define genes that interact with both lin-12 and glp-1 in Caenorhabditis elegans [LiteratureReference:2032748] Deficiency of suppressor enhancer Lin12 1 like (SEL1L) in mice leads to systemic endoplasmic reticulum stress and embryonic lethality
modified	[InstanceEdit:2121213] Orlic-Milacic, M, 2012-02-13 [InstanceEdit:8944184] Orlic-Milacic, Marija, 2016-11-03 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Sel1l negatively regulates Pre-Notch exit from endoplasmic reticulum
output	[CandidateSet:2023163] Glc,Fuc-Pre-Notch [Golgi membrane] [Mus musculus]
regulatedBy	[NegativeRegulation:2032751] Negative regulation by 'Sel1l [endoplasmic reticulum membrane]'
regulationReference	[RegulationReference:9641560] Negative regulation by 'Sel1l [endoplasmic reticulum membrane]' SEL1L deficiency impairs growth and differentiation of pancreatic epithelial cells
releaseDate	2012-03-13
reviewed	[InstanceEdit:2121207] Haw, R, 2012-02-06
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48892] Mus musculus
stableIdentifier	[StableIdentifier:2158150] R-MMU-2032750.5
summation	[Summation:2032752] Sel1l encodes an endoplasmic reticulum membrane protein that...
(inferredFrom)	[BlackBoxEvent:1912374] Transport of NOTCH precursor to Golgi [Homo sapiens]
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No pathways have been reviewed or authored by Sel1l negatively regulates Pre-Notch exit from endoplasmic reticulum (2032750)