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Details on Person On recruitment to plasma membrane PLC-gamma1 then hydrolyses...
| Class:Id | Summation:203260 |
|---|---|
| _displayName | On recruitment to plasma membrane PLC-gamma1 then hydrolyses... |
| _timestamp | 2017-04-06 15:47:39 |
| created | [InstanceEdit:203257] Garapati, P V, 2007-11-12 15:37:54 |
| literatureReference | [LiteratureReference:202392] The mechanism of phospholipase C-gamma1 regulation |
| modified | [InstanceEdit:203778] Garapati, P V, 2007-11-16 10:40:11 [InstanceEdit:8984457] Duenas, Corina, 2017-04-06 |
| text | On recruitment to plasma membrane PLC-gamma1 then hydrolyses PIP2 producing two second messengers, diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). IP3 induces a transient increase in intracellular free Ca++, while DAG is a direct activator of protein kinase C (PKC theta). These process have been implicated in many cellular physiological functions like cell proliferation, cell growth and differentiation. |
| (summation) | [Reaction:202407] PLC-gamma1 hydrolyses PIP2 [Homo sapiens] |
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No pathways have been reviewed or authored by On recruitment to plasma membrane PLC-gamma1 then hydrolyses... (203260)
