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Details on Person Biochemical analysis of pathogenic ligand-dependent FGFR2 mutations suggests distinct pathophysiological mechanisms for craniofacial and limb abnormalities

Class:Id	LiteratureReference:2029802
_displayName	Biochemical analysis of pathogenic ligand-dependent FGFR2 mutations suggests distinct pathophysiological mechanisms for craniofacial and limb abnormalities
_timestamp	2012-01-04 22:04:01
author	[Person:190246] Ibrahimi, OA [Person:184185] Zhang, F [Person:190909] Eliseenkova, AV [Person:190095] Itoh, N [Person:2011811] Linhardt, RJ [Person:111044] Mohammadi, M
created	[InstanceEdit:2029803] Rothfels, K, 2012-01-04
journal	Hum Mol Genet
pages	2313-24
pubMedIdentifier	15282208
title	Biochemical analysis of pathogenic ligand-dependent FGFR2 mutations suggests distinct pathophysiological mechanisms for craniofacial and limb abnormalities
volume	13
year	2004
(literatureReference)	[Pathway:1839126] FGFR2 mutant receptor activation [Homo sapiens] [Reaction:2012074] FGFR3c P250R mutant binds to ligand with enhanced affinity [Homo sapiens] [Reaction:2023451] FGFR1c P252X mutants bind ligand with enhanced affinity [Homo sapiens] [Reaction:2033472] FGFR2c mutants bind an expanded range of ligands [Homo sapiens] [Reaction:2033474] FGFR2b mutants bind an expanded range of ligands [Homo sapiens] [Pathway:2033519] Activated point mutants of FGFR2 [Homo sapiens] [Pathway:5655332] Signaling by FGFR3 in disease [Homo sapiens] [DefinedSet:2065925] FGFR2b mutant-binding FGFs [extracellular region] [Homo sapiens] [EntityWithAccessionedSequence:2071931] FGFR2c A315S [plasma membrane] [Homo sapiens]
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