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Details on Person Production of AA by iPLA2 upon FCGR activation

Class:Id	BlackBoxEvent:2029475
_displayName	Production of AA by iPLA2 upon FCGR activation
_doRelease	TRUE
_timestamp	2024-03-05 18:01:06
authored	[InstanceEdit:2029483] Garapati, P V, 2012-01-04
catalystActivity	[CatalystActivity:2029259] hydrolase activity of PLA2G6 [cytosol]
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:2029474] Garapati, P V, 2012-01-04
edited	[InstanceEdit:2029483] Garapati, P V, 2012-01-04
input	[SimpleEntity:29356] H2O [cytosol] [SimpleEntity:426925] PC [endoplasmic reticulum membrane]
literatureReference	[LiteratureReference:2028783] Immunoglobulin G-mediated phagocytosis activates a calcium-independent, phosphatidylethanolamine-specific phospholipase [LiteratureReference:9863887] Fc receptor-mediated phagocytosis occurs in macrophages at exceedingly low cytosolic Ca2+ levels [LiteratureReference:2028788] Protein kinase C and a calcium-independent phospholipase are required for IgG-mediated phagocytosis by Mono-Mac-6 cells
modified	[InstanceEdit:2197699] Garapati, P V, 2012-04-13 [InstanceEdit:2248843] Garapati, P V, 2012-05-14 [InstanceEdit:2272655] Garapati, P V, 2012-05-25 [InstanceEdit:2429700] Garapati, P V, 2012-08-09 [InstanceEdit:2457636] Garapati, P V, 2012-08-27 [InstanceEdit:3132781] Garapati, P V, 2013-02-13 [InstanceEdit:8854535] D'Eustachio, Peter, 2016-01-27 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 [InstanceEdit:9863893] Shamovsky, Veronica, 2024-03-05
name	Production of AA by iPLA2 upon FCGR activation
output	[SimpleEntity:428981] LPC [endoplasmic reticulum membrane] [SimpleEntity:140356] AA [endoplasmic reticulum lumen]
releaseDate	2013-03-12
reviewed	[InstanceEdit:2248842] Rosales, C, 2012-05-14
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:3200542] R-HSA-2029475.4
summation	[Summation:2028847] Several members of phospholipase A (PLA) are involved in pha...
(hasEvent)	[Pathway:2029485] Role of phospholipids in phagocytosis [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9783574] Update Tracker - [BlackBoxEvent:2029475] Production of AA by iPLA2 upon FCGR activation - v56:[add_removeInput] [_UpdateTracker:9864144] Update Tracker - [BlackBoxEvent:2029475] Production of AA by iPLA2 upon FCGR activation - v88:[add_removeLiteratureReference, modifyText]
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No pathways have been reviewed or authored by Production of AA by iPLA2 upon FCGR activation (2029475)