Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Details on Person (WASPs, WAVE):G-actin:ARP2/3 binds F-actin

Class:Id	Reaction:2029466
_displayName	(WASPs, WAVE):G-actin:ARP2/3 binds F-actin
_doRelease	TRUE
_timestamp	2020-02-06 10:14:54
authored	[InstanceEdit:434636] Jupe, S, 2009-09-02
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:2029463] Garapati, P V, 2012-01-04
edited	[InstanceEdit:2029483] Garapati, P V, 2012-01-04 [InstanceEdit:5671747] Orlic-Milacic, Marija, 2015-02-02
input	[Complex:442565] WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] [Homo sapiens] [Polymer:201877] F-actin [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:2197711] The Arp2/3 complex nucleates actin filament branches from the sides of pre-existing filaments [LiteratureReference:2197704] Mechanism of filament nucleation and branch stability revealed by the structure of the Arp2/3 complex at actin branch junctions [LiteratureReference:2028869] The interaction of Arp2/3 complex with actin: nucleation, high affinity pointed end capping, and formation of branching networks of filaments [LiteratureReference:2028852] ATP hydrolysis on actin-related protein 2/3 complex causes debranching of dendritic actin arrays [LiteratureReference:2028835] Regulation of actin assembly associated with protrusion and adhesion in cell migration [LiteratureReference:418750] Signalling to actin assembly via the WASP (Wiskott-Aldrich syndrome protein)-family proteins and the Arp2/3 complex
modified	[InstanceEdit:2197699] Garapati, P V, 2012-04-13 [InstanceEdit:2248843] Garapati, P V, 2012-05-14 [InstanceEdit:2263488] Garapati, P V, 2012-05-21 [InstanceEdit:2272655] Garapati, P V, 2012-05-25 [InstanceEdit:2429700] Garapati, P V, 2012-08-09 [InstanceEdit:2457636] Garapati, P V, 2012-08-27 [InstanceEdit:3132781] Garapati, P V, 2013-02-13 [InstanceEdit:5674559] Orlic-Milacic, Marija, 2015-02-12 [InstanceEdit:9670158] Murillo, Julieth, 2019-12-05 [InstanceEdit:9673426] Murillo, Julieth, 2020-01-07 [InstanceEdit:9675994] Murillo, Julieth, 2020-02-06 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	(WASPs, WAVE):G-actin:ARP2/3 binds F-actin
output	[Complex:2029140] Mother filament:branching complex [cytosol] [Homo sapiens]
precedingEvent	[Reaction:442592] WASPs or WAVEs activate the ARP2/3 complex [Homo sapiens] [Reaction:430180] NCK recruits WASP [Homo sapiens] [Reaction:2197698] Src phosphorylate WASP,N-WASP [Homo sapiens] [Reaction:2130194] ABL phosphorylates WAVEs [Homo sapiens]
releaseDate	2013-03-12
reviewed	[InstanceEdit:2248842] Rosales, C, 2012-05-14 [InstanceEdit:5668821] Rivero Crespo, Francisco, 2014-12-26
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:3200467] R-HSA-2029466.3
summation	[Summation:442562] Once activated, the ARP2/3 complex nucleates new actin filam...
(hasEvent)	[Pathway:2029482] Regulation of actin dynamics for phagocytic cup formation [Homo sapiens] [Pathway:5663213] RHO GTPases Activate WASPs and WAVEs [Homo sapiens] [Pathway:9664422] FCGR3A-mediated phagocytosis [Homo sapiens]
(precedingEvent)	[Reaction:2197690] Detachment of WASP/WAVE [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9785328] Update Tracker - [Reaction:2029466] (WASPs, WAVE):G-actin:ARP2/3 binds F-actin - v52:[modifyText]
[Change default viewing format]

No pathways have been reviewed or authored by (WASPs, WAVE):G-actin:ARP2/3 binds F-actin (2029466)