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Details on Person clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane]

Class:Id	Complex:2029158
_displayName	clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane]
_timestamp	2013-02-28 11:31:18
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:2029143] Garapati, P V, 2012-01-04
hasComponent	[Complex:2029128] clustered IgG-Ag:p-FCGRs [plasma membrane] [Homo sapiens] [Complex:173552] Antigen:IgG [plasma membrane] [Homo sapiens] [OtherEntity:173548] Antigen [plasma membrane] [Complex:182629] IgG [extracellular region] [Homo sapiens] [DefinedSet:197021] Ig Antibody Light Chain [extracellular region] [Homo sapiens] [DefinedSet:197021] Ig Antibody Light Chain [extracellular region] [Homo sapiens] [Complex:1591203] IgG Heavy Chain [extracellular region] [Homo sapiens] [DefinedSet:197042] Ig Heavy Chain V Region [extracellular region] [Homo sapiens] [DefinedSet:1584646] IgG C region [extracellular region] [Homo sapiens] [Complex:1591203] IgG Heavy Chain [extracellular region] [Homo sapiens] [DefinedSet:197042] Ig Heavy Chain V Region [extracellular region] [Homo sapiens] [DefinedSet:1584646] IgG C region [extracellular region] [Homo sapiens] [DefinedSet:2029104] p-FCGRs [plasma membrane] [Homo sapiens] [EntityWithAccessionedSequence:1861712] p-6Y-SYK [cytosol] [Homo sapiens]
isChimeric	FALSE
modified	[InstanceEdit:2263503] Garapati, P V, 2012-05-21
name	clustered IgG-Ag:p-FCGRs:p-6Y-SYK
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:3202608] R-HSA-2029158.1
(hasComponent)	[Complex:2029130] CRKII:DOCK180:ELMO complex recruited to phagocytic cup [plasma membrane] [Homo sapiens] [Complex:2029131] clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-VAV [plasma membrane] [Homo sapiens] [Complex:2029133] clustered IgG-Ag:p-FCGRs:p-6Y-SYK:VAV [plasma membrane] [Homo sapiens] [Complex:2029137] clustered IgG-Ag:p-FCGRs:p-6Y-SYK:PLCG [plasma membrane] [Homo sapiens] [Complex:2029149] PI3K:p-6Y-SYK [plasma membrane] [Homo sapiens] [Complex:2029156] clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-3Y-PLCG [plasma membrane] [Homo sapiens]
(input)	[Reaction:2029270] Recruitment of PLCgamma to membrane [Homo sapiens] [Reaction:2029273] PI3K binds to p-6Y-SYK [Homo sapiens] [Reaction:2029458] Recruitment of VAV1 to p-6Y-SYK [Homo sapiens] [Reaction:2029470] Release of activated SYK from ITAM [Homo sapiens] [Reaction:2197697] Recruitment of CRKII:DOCK180:ELMO complex to FCGR [Homo sapiens]
(output)	[Reaction:2029272] Release of PLCG from FCGR [Homo sapiens] [Reaction:2029449] Phosphorylation of SYK by Src kinases [Homo sapiens]
(physicalEntity)	[CatalystActivity:2029260] protein tyrosine kinase activity of clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane]
(updatedInstance)	[_UpdateTracker:9895458] Update Tracker - [Complex:2029158] clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] - v59:[updateContainedComponent] [_UpdateTracker:9895926] Update Tracker - [Complex:2029158] clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] - v60:[updateContainedComponent] [_UpdateTracker:9899957] Update Tracker - [Complex:2029158] clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] - v67:[updateContainedComponent] [_UpdateTracker:9900914] Update Tracker - [Complex:2029158] clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] - v71:[updateContainedComponent] [_UpdateTracker:9953879] Update Tracker - [Complex:2029158] clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] - v93:[updateContainedComponent]
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No pathways have been reviewed or authored by clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (2029158)