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Details on Person Phosphorylation of MOB1A and B by p-STK3(MST2)/N

Class:Id	Reaction:2028675
_displayName	Phosphorylation of MOB1A and B by p-STK3(MST2)/N
_doRelease	TRUE
_timestamp	2012-03-01 11:20:32
authored	[InstanceEdit:2085531] D'Eustachio, P, 2012-02-03
catalystActivity	[CatalystActivity:2028693] protein serine/threonine kinase activity of p-STK3/N:p-SAV1 [cytosol]
catalystActivityReference	[CatalystActivityReference:9643212] protein serine/threonine kinase activity of p-STK3/N:p-SAV1 [cytosol] MST, a physiological caspase substrate, highly sensitizes apoptosis both upstream and downstream of caspase activation
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:2028678] D'Eustachio, P, 2011-12-30
edited	[InstanceEdit:2028654] D'Eustachio, P, 2011-12-30
input	[SimpleEntity:113592] ATP [cytosol] [SimpleEntity:113592] ATP [cytosol] [DefinedSet:2028544] MOB1 [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:2028689] MST, a physiological caspase substrate, highly sensitizes apoptosis both upstream and downstream of caspase activation
modified	[InstanceEdit:2028699] D'Eustachio, P, 2011-12-30 [InstanceEdit:2085534] D'Eustachio, P, 2012-02-03 [InstanceEdit:9643047] Wu, G, 2019-04-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Phosphorylation of MOB1A and B by p-STK3(MST2)/N
output	[SimpleEntity:29370] ADP [cytosol] [SimpleEntity:29370] ADP [cytosol] [DefinedSet:2028620] p-MOB1 [cytosol] [Homo sapiens]
precedingEvent	[Reaction:2028697] Cleavage of p-STK3 (p-MST2) by caspase 3 [Homo sapiens] [Reaction:2028591] Phosphorylation of STK3 (MST2) and SAV1 by STK3 [Homo sapiens]
releaseDate	2012-03-13
reviewed	[InstanceEdit:2085532] Sudol, M, 2012-02-03
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2158045] R-HSA-2028675.3
summation	[Summation:2028676] Cytosolic MOB1A and MOB1B are phosphorylated by phospho-STK3...
(hasEvent)	[Pathway:2028269] Signaling by Hippo [Homo sapiens]
(precedingEvent)	[Reaction:2028626] Phosphorylated MOB1A proteins associate with LATS proteins [Homo sapiens]
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No pathways have been reviewed or authored by Phosphorylation of MOB1A and B by p-STK3(MST2)/N (2028675)