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Details on Person Integrin alpha4beta1 binds JAM2:JAM3

Class:IdReaction:202706
_displayNameIntegrin alpha4beta1 binds JAM2:JAM3
_doReleaseTRUE
_timestamp2020-06-02 13:59:04
authored[InstanceEdit:203275] Ouwehand, W.H., 2007-11-12 16:45:54
compartment[Compartment:876] plasma membrane
created[InstanceEdit:202725] de Bono, B, 2007-11-11 16:10:42
input[Complex:198201] ITGA4:ITGB1 [plasma membrane] [Homo sapiens]
[Complex:202761] JAM2:JAM3 [plasma membrane] [Homo sapiens]
literatureReference[LiteratureReference:202753] The role of junctional adhesion molecules in vascular inflammation
[LiteratureReference:203312] JAM2 interacts with alpha4beta1. Facilitation by JAM3.
modified[InstanceEdit:202758] de Bono, B, 2007-11-11 17:12:16
[InstanceEdit:203161] de Bono, B, 2007-11-12 15:22:51
[InstanceEdit:203271] de Bono, B, 2007-11-12 16:48:44
[InstanceEdit:203314] de Bono, B, 2007-11-12 17:46:57
[InstanceEdit:203956] de Bono, B, 2007-11-21 12:30:25
[InstanceEdit:204045] de Bono, B, 2007-11-22 07:10:13
[InstanceEdit:213345] Gopinathrao, G, 2008-02-25 21:36:16
[InstanceEdit:215251] Gopinathrao, G, 2008-02-27 21:37:06
[InstanceEdit:266426] Garapati, P V, 2008-05-07 11:09:42
[InstanceEdit:266427] Garapati, P V, 2008-05-07 11:11:11
[InstanceEdit:4205070] Jupe, S, 2013-08-15
[InstanceEdit:5603463] Jupe, Steve, 2014-07-02
[InstanceEdit:9690529] Jassal, Bijay, 2020-06-02
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameIntegrin alpha4beta1 binds JAM2:JAM3
output[Complex:202759] integrin alpha4beta1:JAM2:JAM3 [plasma membrane] [Homo sapiens]
precedingEvent
regulatedBy[NegativeRegulation:9690528] Negative regulation by 'ITGA4:ITGB1:natalizumab [plasma membrane]'
regulationReference[RegulationReference:9690530] Negative regulation by 'ITGA4:ITGB1:natalizumab [plasma membrane]' Anti-alpha4 integrin therapy for multiple sclerosis: mechanisms and rationale
releaseDate2007-12-11
reviewed[InstanceEdit:266386] Yamada, K, Humphries, MJ, Hynes, R, 2008-05-07 08:53:37
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:358378] R-HSA-202706.3
summation[Summation:203316] Several key IgSF cell adhesion molecules engage integrin and...
(hasEvent)[Pathway:202733] Cell surface interactions at the vascular wall [Homo sapiens]
[Pathway:216083] Integrin cell surface interactions [Homo sapiens]
(updatedInstance)[_UpdateTracker:9776885] Update Tracker - [Reaction:202706] Integrin alpha4beta1 binds JAM2:JAM3 - v74:[addRegulator, modifyText]
[_UpdateTracker:9786064] Update Tracker - [Reaction:202706] Integrin alpha4beta1 binds JAM2:JAM3 - v50:[add_removeInput, modifyText, removeRegulator]
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No pathways have been reviewed or authored by Integrin alpha4beta1 binds JAM2:JAM3 (202706)