Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling

Class:IdLiteratureReference:202618
_displayNameSmurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling
_timestamp2007-11-07 13:14:29
author[Person:202533] Lin, X
[Person:202634] Liang, M
[Person:202641] Feng, XH
created[InstanceEdit:202635] Jassal, B, 2007-11-07 13:11:04
journalJ Biol Chem
pages36818-22
pubMedIdentifier11016919
titleSmurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling
volume275
year2000
(literatureReference)[BlackBoxEvent:201445] Ubiquitin-dependent degradation controls basal levels of R-Smad1/5/8 [Homo sapiens]
[BlackBoxEvent:209052] Ubiquitinated and phosphorylated MAD/SMOX is degraded by the proteasome complex [Drosophila melanogaster]
[BlackBoxEvent:209064] Ubiquitinated and phosphorylated human SMAD2 binds to and is degraded by the proteasome complex [Homo sapiens]
[Reaction:209111] Human phosphorylated SMAD2 is ubiquitinated and dissociates from SMURF2 [Homo sapiens]
[Reaction:209121] LACK binds to Phospho MAD/SMOX [Drosophila melanogaster]
[Reaction:209145] Phosphorylated MAD/SMOX is ubiquitinated and dissociates from LACK [Drosophila melanogaster]
[Change default viewing format]
No pathways have been reviewed or authored by Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling (202618)