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Details on Person Expression of FABP2

Class:Id	BlackBoxEvent:2026095
_displayName	Expression of FABP2
_timestamp	2018-10-31 13:56:04
authored	[InstanceEdit:2026092] May, B, 2011-12-21
compartment	[Compartment:7660] nucleoplasm [Compartment:70101] cytosol
created	[InstanceEdit:2026094] May, B, 2011-12-22
edited	[InstanceEdit:2026092] May, B, 2011-12-21
input	[EntityWithAccessionedSequence:5640183] FABP2 gene [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:2026054] Analysis of the transcriptional regulation of the FABP2 promoter haplotypes by PPARgamma/RXRalpha and Oct-1 [LiteratureReference:2026066] The association of fatty acid-binding protein 2 A54T polymorphism with postprandial lipemia depends on promoter variability
modified	[InstanceEdit:5640212] May, Bruce, 2014-11-16 [InstanceEdit:8879177] Wu, G, 2016-07-15 [InstanceEdit:9606200] Wu, G, 2018-04-19 [InstanceEdit:9626992] May, Bruce, 2018-10-31 [InstanceEdit:9641190] Wu, G, 2019-04-04 [InstanceEdit:9733355] Wu, Guanming, 2021-06-04
name	Expression of FABP2
output	[EntityWithAccessionedSequence:2026074] FABP2 [cytosol] [Homo sapiens]
precedingEvent	[Reaction:381309] PPARG:RXRA heterodimer binds to fatty acid-like ligands [Homo sapiens] [Reaction:381290] PPARG:RXRA heterodimer binds to PPARG corepressors [Homo sapiens] [BlackBoxEvent:2026091] FABP4 transports lipids Into the nucleus [Homo sapiens]
regulatedBy	[PositiveGeneExpressionRegulation:2026098] Positive gene expression regulation by 'PPARG:Fatty Acid:RXRA:Mediator:Coactivator Complex [nucleoplasm]' [PositiveGeneExpressionRegulation:8940255] Positive gene expression regulation by 'PPARG isoform1:NCOA4:FABP2 gene [nucleoplasm]'
regulationReference	[RegulationReference:9642350] Positive gene expression regulation by 'PPARG:Fatty Acid:RXRA:Mediator:Coactivator Complex [nucleoplasm]' Analysis of the transcriptional regulation of the FABP2 promoter haplotypes by PPARgamma/RXRalpha and Oct-1 [RegulationReference:9642821] Positive gene expression regulation by 'PPARG isoform1:NCOA4:FABP2 gene [nucleoplasm]' Identification of ARA70 as a ligand-enhanced coactivator for the peroxisome proliferator-activated receptor gamma
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:8929009] R-HSA-2026095.1
summation	[Summation:2026040] The FABP2 gene is transcribed to yield mRNA and the mRNA is ... [Summation:8942167] As inferred from the mouse Pparg, PPARG interacts with NCOA4... [Summation:8942165] The PPARG:RXRA heterodimer binds the promoter of the FABP2 g...
(hasEvent)	[Pathway:381340] Transcriptional regulation of white adipocyte differentiation [Homo sapiens]
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No pathways have been reviewed or authored by Expression of FABP2 (2026095)