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Details on Person p-S243-NFATC2 [nucleoplasm]

Class:Id	EntityWithAccessionedSequence:2025894
_displayName	p-S243-NFATC2 [nucleoplasm]
_timestamp	2012-03-01 11:57:45
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:2025849] May, B, 2011-12-20
endCoordinate	925
hasModifiedResidue	[ModifiedResidue:2025997] O-phospho-L-serine at 243
inferredFrom	[EntityWithAccessionedSequence:2025858] p-S245-Nfatc2 [nucleoplasm] [Mus musculus]
name	p-S243-NFATC2 Nuclear factor of activated T-cells, cytoplasmic 2 NFAC2_HUMAN NFATC2
referenceEntity	[ReferenceGeneProduct:60121] UniProt:Q13469 NFATC2 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:2159684] R-HSA-2025894.1
startCoordinate	1
(activeUnit)	[PositiveGeneExpressionRegulation:9976128] Positive gene expression regulation by 'GATA3:CHD4:EP300:p-S243-NFATC2:FOS:JUN:KLF13:MAF:IL4 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:9976145] Positive gene expression regulation by 'MLL1:MEN1:p-Y641-STAT6:p-S243-NFATC2:Notch1,2 Coactivator:GATA3 gene [nucleoplasm]'
(hasComponent)	[Complex:9976109] MLL1:MEN1:p-Y641-STAT6:p-S243-NFATC2:Notch1,2 Coactivator:GATA3 gene [nucleoplasm] [Homo sapiens] [Complex:9976142] GATA3:CHD4:EP300:p-S243-NFATC2:FOS:JUN:KLF13:MAF:IL4 gene [nucleoplasm] [Homo sapiens] [Complex:9976378] GATA3:CHD4:EP300:p-S243-NFATC2:IL13 gene [nucleoplasm] [Homo sapiens]
(hasMember)	[DefinedSet:2025852] Dephosphorylated NFATC1,2,3 [nucleoplasm] [Homo sapiens]
(input)	[Reaction:9976117] STAT6, NFATC2 (NFAT1), and NICD1,2 bind the GATA3 gene and cause displacement of repressor complexes (PRC1, RBPJ:NCOR) by activator complexes (MLL1, RBPJ:NICD1,2) [Homo sapiens] [Reaction:9976129] GATA3, CHD4, EP300, NFATC2 (NFAT1), FOS:JUN (AP-1), KLF13, and MAF bind the IL4 gene [Homo sapiens] [Reaction:9976381] GATA3, CHD4, EP300, and NFATC2 bind the IL13 gene [Homo sapiens]
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No pathways have been reviewed or authored by p-S243-NFATC2 [nucleoplasm] (2025894)